en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background:</span></span></span></span></span></span> <span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">Ovarian Malignant M&uuml;llerian Mixed Tumor (MMMT), also named ovarian carcinosarcoma (OCS), is a rare and aggressive biphasic malignancy with malignant epithelial and mesenchymal components. Advanced magnetic resonance imaging (MRI) techniques like quantitative T2 mapping enable non-invasive tissue microstructural assessment, their diagnostic value for ovarian MMMT requires further elucidation with clinical case evidence. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Case presentation: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">A 78-year-old female presented with chronic constipation and a pelvic mass. Imaging revealed a large, heterogeneous pelvic mass with peritoneal and omental involvement. Quantitative MRI analysis revealed a T2 mapping value of 148&plusmn;18 ms and a low apparent diffusion coefficient (ADC) value of 0.98&plusmn;0.08&times;10</span></span></span></span><span lang="en-GB" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">^-3</span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB"> mm</span></span></span></span><span lang="en-GB" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">²</span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">/s. Histopathological examination confirmed ovarian MMMT with heterologous chondrosarcoma components. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Conclusion: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">This case demonstrates that quantitative MRI parameters, especially T2 mapping, can reflect the high-grade malignant microstructural features of ovarian MMMT. T2 mapping serves as a valuable non-invasive biomarker for characterizing this rare gynecological malignancy, potentially aiding in the differentiation of benign and malignant ovarian lesions and assessment of tumor aggressiveness.</span></span></span></span></span></span></span></span></span></span></div> Ovarian malignant Müllerianmixed tumor, carcinosarcoma, magnetic resonance imaging, t2 mapping, apparent diffusion coefficient. 567 572 http://ijrr.com/browse.php?a_code=A-10-1-1540&slc_lang=en&sid=1 X. Wang 7900319475328460033799 7900319475328460033799 No Department of Radiology, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China G. Sun 7900319475328460033800 7900319475328460033800 No Department of Radiology, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China H. Zhang 7900319475328460033801 7900319475328460033801 No Department of Ultrasound, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China M. Chen chenminzhi_zhuhai@163.com 7900319475328460033802 7900319475328460033802 Yes Department of Ultrasound, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China