en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background:</span></span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">This study aims to assess the liver dose received in the absence of explicit dose considerations during right chest wall radiotherapy planning for three different treatment techniques and to contribute to thr limited literature on this topic. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A total of 20 patients with indications for radiotherapy of the right chest wall following mastectomy were selected. After tomography scan images were sent to the Treatment Planning System (TPS), where a radiation oncologist delineated the target volumes and critical structures. Subsequently, a medical physicist created treatment plans utilizing three techniques. The dosimetric parameters were evaluated and compared for different treatment techniques. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The field-in-field (FIF) technique resulted in the lowest mean liver dose and V10 values (p<0.001). No significant difference was observed between helical tomotherapy (HT) and intensity-modulated radiotherapy (IMRT) techniques regarding average liver doses and V10 values. The FIF treatment technique also showed the lowest V20 value. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusions: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">In right breast radiotherapy, when comparing liver doses across different treatment plans excluding the liver, the FIF technique demonstrated significantly better results in terms of average liver dose than the other two treatment techniques. It was concluded that liver dose should be taken into account during treatment planning.</span></span></span></span></span></span></span></span></span></div> Radiotherapy planning, right chest wall, liver dose, field-in-field, intensity-modulated radiotherapy, helical tomotherapy. 671 677 http://ijrr.com/browse.php?a_code=A-10-1-1562&slc_lang=en&sid=1 H. Demir hikmettindemir@yyu.edu.tr 7900319475328460034252 7900319475328460034252 Yes Van Yuzuncu Yil University, Department of Radiation Oncology, 65080, Van, Turkey B.B. Yavuz 7900319475328460034253 7900319475328460034253 No Necmettin Erbakan University, Department of Radiation Oncology,42100, Konya, Turkey O.V. Gul 7900319475328460034254 7900319475328460034254 No Selcuk University, Department of Radiation Oncology, 42100, Konya, Turkey T. Cakir 7900319475328460034255 7900319475328460034255 No Van Yuzuncu Yil University, Department of Biophysics & Radiation Oncology, 65080, Van, Turkey