International Journal of Radiation Research

en Relative peripheral retinal defocus patterns assessed by multispectral refractive topography and their association with myopia-related ocular parameters in early school-aged children Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: Relative peripheral retinal defocus has been implicated in refractive development, but multispectral refractive topography (MRT) patterns in early school-aged children remain incompletely characterized. This study evaluated MRT-derived relative peripheral retinal defocus patterns and their associations with myopia-related ocular parameters. Materials and Methods: This study included 115 children, aged 5-8 years, who underwent cycloplegic autorefraction, optical biometry, and MRT between July and November 2024. Right-eye data were analyzed. Spherical equivalent (SE), axial length (AL), mean keratometry (Km), and the axial length/corneal radius ratio (AL/CR) were calculated. Relative peripheral retinal defocus parameters were measured within a 53°retinal field and classified into volcanic mouth, hemiolateral upturned, saddle, and relatively flat patterns. Correlations and between-group differences were analyzed. Results: Diopter sphere (DS) was negatively correlated with total retinal defocus value (TRDV), 0-30°defocus (RDV-30), 0-45°defocus (RDV-45), 15-30°defocus (RDV-15-30), 30-45°defocus (RDV-30-45), and inferior defocus value (RDV-I) (all P<0.05). SE was negatively correlated with RDV-30, RDV-45, RDV-15-30, RDV-30-45, and RDV-I (all P<0.05). The hemiolateral upturned pattern was the most frequent pattern (31.30%), followed by the volcanic mouth (26.09%), saddle (22.61%), and relatively flat (20.00%) patterns. SE, DS, AL, AL/CR, and regional defocus parameters differed significantly among patterns (P<0.05). Conclusion: MRT-derived relative peripheral retinal defocus patterns were associated with refractive status and ocular biometry in early school-aged children. The volcanic mouth pattern was linked to a more myopic ocular profile, whereas the relatively flat pattern was linked to a more hyperopic profile.</div> Early school-aged children, myopia, relative peripheral retinal defocus, multispectral refractive topography, ocular biometry. 935 942 http://ijrr.com/browse.php?a_code=A-10-1-1597&slc_lang=en&sid=1 J. Wang 7900319475328460034551 7900319475328460034551 No Department of Ophthalmology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China Z. Dou 7900319475328460034552 7900319475328460034552 No Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China X. Wang 7900319475328460034553 7900319475328460034553 No Department of Emergency Medicine, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China