[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 16, Issue 4 (10-2018) ::
Int J Radiat Res 2018, 16(4): 421-430 Back to browse issues page
Protective role of ferulic acid against the damaging effect induced by electromagnetic waves on rat liver and intestine tissues
M.S. Tawfik, M. Saif-Elnasr PhD , A.A. Elkady, M.M. Alkady, A.M. Hawas
Health radiation research department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), P.O. Box 29, Nasr City, Cairo, Egypt , mostafa_saif_elnasr@yahoo.com
Abstract:   (1330 Views)
Background: the increasing use of mobile phones in daily life causes many concerns about their effects on human health. Therefore, this work was designed to study the effects of exposure to 1800 MHz electromagnetic waves (EMW) on the liver and intestine of male albino rats and the protective role of ferulic acid (FA) against these harmful effects. Materials and Methods: twenty-four male albino rats were randomly divided into four groups as follows: 1) control group, 2) treated group given FA, 3) irradiated group exposed to 1800 MHz EMW and 4) treated-irradiated group given FA then exposed to EMW. Biochemical analysis and histopathological examination were performed. Results: a significant increase in serum activities of alanine transaminase and aspartate transaminase, and serum levels of interleukin (IL)-6 and tumor necrosis factor-α was shown in the irradiated group, while IL-10 was significantly decreased. There was a significant decrease in lactate dehydrogenase and total antioxidant capacity in the tissues of liver and intestine of this group as well as some histopathological changes. All these serum and tissues parameters and histopathological changes were improved in the group treated with FA before exposure to EMW. Conclusion: prolonged exposure to EMW emitted from mobile phones might produce harmful effects in the liver and intestinal tissues of albino rats. These effects can be prevented by FA administration which may be protective against tissue damage induced by EMW through the suppression of oxidative stress.
Keywords: Mobile phones, electromagnetic waves, liver, intestine, ferulic acid.
Full-Text [PDF 2320 kb]   (285 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Tawfik M, Saif-Elnasr M, Elkady A, Alkady M, Hawas A. Protective role of ferulic acid against the damaging effect induced by electromagnetic waves on rat liver and intestine tissues . Int J Radiat Res. 2018; 16 (4) :421-430
URL: http://ijrr.com/article-1-2396-en.html

Volume 16, Issue 4 (10-2018) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3977