[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 18, Issue 4 (10-2020) ::
Int J Radiat Res 2020, 18(4): 853-862 Back to browse issues page
Dosimetric evaluation of field-in-field and sliding-window IMRT in endometrium cancer patients with a new approach for the conformity index
A. Özseven , E. Elif Özkan
Suleyman Demirel University Research and Application Hospital Department of Radiation Oncology, Isparta, Turkey , alperozseven@sdu.edu.tr
Abstract:   (1988 Views)
Background: Purpose of the study is to evaluate field-in-field (FIF) and sliding-window intensity modulated radiation therapy (SW-IMRT) treatment plans in terms of homogeneity index (HI), conformity index (CI) and normal tissue doses for organs at risk (OAR) in patients with endometrial carcinoma along with deriving a new expression for CI. Materials and Methods: Four different FIF plans with different MLC (multi-leaf collimator) margins and SW-IMRT plan were compared in 20 endometrial cancer patients who underwent adjuvant pelvic radiotherapy with 50.4 Gy in 28 fractions. Normal tissue doses were assessed for OAR from dose volume histograms (DVHs). HI and CI values were calculated according to the reports of International Commission on Radiation Units and Measurements (ICRU)-83, Radiation Therapy Oncology Group (RTOG) 1993 and ICRU-62. A new CI was developed and named CIOPT standing for optimized conformity index. Results: SW-IMRT provided a significantly better CI in comparison to other FIF plans (p< 0.001). Conventional-FIF (C-FIF) was the most homogeneous plan compared to all other FIF plans and SW-IMRT (p≤0.001). The absolute volume of small intestine that received ≥45 Gy (V45) and doses received by a 30% volume of rectum (D30) were dramatically reduced in SW-IMRT (p < 0.001). Conclusion: MLC margins had a substantial influence on OAR doses, HI and CI. A close proximity of CIOPT to 1 indicated that this formulation of CI was a useful plan evaluation tool, which was also compatible with the RTOG 1993 and ICRU-62 reports.
Keywords: Conformity index, endometrium cancer, field-in-field, homogeneity index, IMRT.
Full-Text [PDF 1985 kb]   (1184 Downloads)    
Type of Study: Original Research | Subject: Medical Physics
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Özseven A, Elif Özkan E. Dosimetric evaluation of field-in-field and sliding-window IMRT in endometrium cancer patients with a new approach for the conformity index. Int J Radiat Res 2020; 18 (4) :853-862
URL: http://ijrr.com/article-1-3307-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 18, Issue 4 (10-2020) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.04 seconds with 50 queries by YEKTAWEB 4642