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A survey on stimulatory effects of topical application of radioactive lantern mantle powder on wound healing
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S.M.J. Mortazavi   , M.R. Rahmani , A. Rahnama , A. Saeed-Pour , E. Nouri , N. Hosseini , M.M. Aghaiee |
| , mmortazavi@sums.ac.ir |
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Abstract: (13316 Views) |
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Background: Poorly educated people in some
parts of Iran use burned mantles as a wound
healing medicine. Materials and Methods: To
perform surface area measurement, twenty rats
were divided randomly into two groups of 10
animals each. The first group received topical
burned radioactive lantern mantle powder on the
first to third days after making excision wounds. The
second group received non-radioactive lantern
mantle powder. For histological study, 36 male rats
were randomly divided into two groups of 18
animals each. Full thickness excision wound
(314±31.4 mm2) was made on the dorsal neck in all
animals after inducing general anesthesia. For the
first three days, cases had received topical
application of the radioactive lantern mantle
powder. Finally, to measure the tensile strength, an
incision was made on the dorsal neck of the rats.
Results: Surface area measurement of the wounds
showed a progressive surface reduction in both
groups. Histological study showed a significant
statistically difference between cases and controls
with respect to fibrinoid necrosis and neutrophilic
exudate on days 3 and 14. Considering the
existence of granulated tissue, a significant
difference was observed between case and control
groups on days 3 and 7. Tensile strength study
showed no significant difference between the cases
and controls. Conclusion: Topical use of radioactive
mantle powder can accelerate the healing process
of the wound in rats. |
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| Keywords: Lantern mantle, wound healing, radioactive, thorium. |
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Full-Text [PDF 297 kb]
(2401 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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