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Assessment of bone mineral density with dual energy X-ray absorptiometry in pre- and post-menopausal women
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M.R. Salamat   , N. Rostampour , S. Shanehsazzadeh , M.B. Tavakoli , M. Siavash , T. Almasi |
| , nrostampour@yahoo.com |
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Abstract: (11714 Views) |
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Background: Osteoporosis is a chronic disease
that contributes substantially to decrease physical
activity and decline in the quality of life.
Osteoporosis can be diagnosed easily with the use
of dual-energy X-ray absorptiometry (DXA)
equipment. The aim of this study was to investigate
the magnitude of bone loss on proximal femur and
lumbar spine LS in pre- and post-menopausal
women from Isfahan Osteoporosis Diagnosis Center
(IODC) since 2005. Materials and Methods: Bone
mineral density (BMD) measurements using DXA
have been performed at IODC. 185 pre-menopausal
and 174 early post-menopausal women were
selected randomly. A Norland XR46 system was
used for the investigations. The student t-test was
done to find the difference between the T-scores of
the femoral neck (FN) and lumbar spine (LS) in
pre- and post-menopausal women. Results: Mean
BMDs for the FN and LS in pre-menopausal women
were 0.859 ± 0.136 and 1.012 ± 0.161 and in
post-menopausal women were 0.816 ± 0.119 and
0.919 ± 0.140, respectively. Long-term BMD CVs of
1.0% and 1.2% for the LS and FN were found,
respectively. The differences between the FN and
LS for pre- and post-menopausal women were t = -
9.02, p < 0.05 and t = -3.50, p < 0.05, respectively.
Conclusion: In spite of, the reported lower BMD
T-scores for the LS compared with the FN for
women, we found that the FN had significantly lower
T-score than LS for both pre- and post-menopausal
women. |
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| Keywords: BMD, osteoporosis, proximal femur, lumbar spine, DXA. |
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Full-Text [PDF 226 kb]
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Type of Study: Original Research |
Subject:
Radiation Biology
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