Individual virtual phantom reconstruction for organ dosimetry based on standard available phantoms
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F. Babapour Mofrad , R. Aghaeizadeh Zoroofi , A. Abbaspour Tehrani Fard , Sh. Akhlaghpoor , Y.W. Chen , Y. Sato |
, farshid.mofrad@yahoo.com |
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Abstract: (13045 Views) |
Background: In nuclear medicine application
often it is required to use computational methods for
evaluation of organ absorbed dose. Monte Carlo
simulation and phantoms have been used in many
works before. The shape, size and volume in organs
are varied, and this variation will produce error in
dose calculation if no correction is applied. Materials
and Methods: A computational framework for
constructing individual phantom for dosimetry was
performed on five liver CT scan data sets of Japanese
normal individuals. The Zubal phantom was used as
an original phantom to be adjusted by each individual
data set. This registration was done by Spherical
Harmonics (SH) and Thin-Plate Spline methods.
Hausdorff distance was calculated for each case.
Results: Result of Hausdorff distance for five individual
phantoms showed that before registration ranged
from 140.9 to 192.1, and after registration it
changed to 52.5 to 76.7. This was caused by index
similarity ranged from %56.4 to %70.3. Conclusion: A
new and automatic three-dimensional (3D) phantom
construction approach was suggested for individual
internal dosimetry simulation via Spherical Harmonics
(SH) and Thin-Plate Spline methods. The results
showed that the individual comparable phantom can
be calculated with acceptable accuracy using
geometric registration. This method could be used for
race-specific statistical phantom modeling with major
application in nuclear medicine for absorbed dose
calculation. Iran. J. Radiat. Res., 2010 7 (4): 201-206 |
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Keywords: Dosimetry, individual phantom, thin-plate spline, Monte Carlo simulation, spherical harmonics. |
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Full-Text [PDF 365 kb]
(2911 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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