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Showing 3 results for Omran
M. Najafi, Dr. H.a. Nedaie, A. Lahooti, R. Omranipour, N. Nafissi, M.e. Akbari, A. Olfatbakhsh, A. Kaviani, N. Alavi,
Volume 10, Issue 1 (6-2012)
Abstract
Background: Sentinel node biopsy (SLNB) is the
standard of care for breast cancer treatment and it is
getting wide acceptance in Iran. The radiation safety
of the procedure has been investigated under
controlled conditions, but the standard dose of radiotracer
and techniques are not always observed in the
community setting. The aim of this study was to
assess the magnitude of the absorbed doses of radiation
to the hands of operating surgeons. Materials
and Methods: Twenty consecutive SLNB procedures
were studied. Radiation dose to the hands of the
surgeons was measured by placing lithium fluoride
thermoluminescent dosimeters (TLDs) in the
surgeons' glove. The radiation dose to the abdomen
and thyroid area was measured by placing TLDs at
these areas. The injected dose of radiotracer, the
time interval to the surgery and the duration of the
surgery were recorded. Results: The injected dose of
radiotracer ranged from 0.1 to 5 mCi. The highest
absorbed dose was recorded by TLD, placed on the
non-dominant hand third finger (189.1 μSv). Mean
recorded doses were higher for non-dominant hand
second finger (53.49 ± 24.60 μSv). The measured
absorbed doses for the abdominal and thyroid area
were lower than those for the fingers. Conclusion:
This study has confirmed the procedure safety, even
with high dose of radiotracer. Nevertheless, it is
advisable to use the lowest dose of the radiotracer to
avoid the waste of resources. Iran. J. Radiat. Res.,
2012 10(1): 53-57
Dr. A. Khalil, H. Omran, S. Habeel, F. Alsheikh,
Volume 19, Issue 3 (7-2021)
Abstract
Background: In this work, a low-dose rate (100mGy/min of whole body gamma irradiation fractionated (0.5, 1, and 2Gy) was used to study the effects of cumulative doses on the expression of target genes implicated in the intestinal inflammatory process in high fat diet (HFD) wistar rats. Material and Methods: Total RNA was extracted and the expression of target genes was measured in the four intestinal segments (duodenum, jejunum, ileum and colon) of HFD Wistar rats. Results: Our in-vivo results in the four intestinal segments (duodenum, jejunum, ileum, and colon) demonstrated that gamma irradiation exposure in HFD rats amplified the low-grade inflammatory state already induced by HFD. This phenomenon occurs through the induction of pro-inflammatory cytokines mainly the tumor necrosis factor-alpha (TNFα) and interleukin 6 (IL-6) or via overexpression/increasing of anti-inflammatory response involved interleukin 10 (IL-10) and the growth factor β (TGFβ) overall the bowel segments. Results suggested that whole body gamma irradiation might have dual roles, first, engraving the inflammatory state already initiated by HFD, and second, an over expressed anti-inflammatory response via anti-inflammatory cytokines mainly IL-10 and TGFβ. Conclusion: The current study clearly demonstrated the important role of the gut in HFD rats during fractionated whole body irradiation (FWBGI) and indicated that TGFβ and IL-10 may be the target in whole body radiotherapy as a mechanism to recompense for the imbalance between pro-inflammatory and anti-inflammatory cytokines.
Mb B. Al Omran Al Omran, A. Mohamed Mehad Mohamed Mehad, S. Matoi, S.m. Abdul Qadir, A. Peluola, R. O’sullivan, N. Dayoub,
Volume 20, Issue 4 (10-2022)
Abstract
Background: This study was designed to evaluate the matching percentage among findings of the ultrasound scans (USS) to the magnetic resonance imaging (MRI) in women with fibroids. Materials and Methods: This descriptive, retrospective study was conducted from January 2016 to December 2018. This study includes 205 female patients referred from the Gynaecological Department to the Radiological Department in the Bahrain Defense Force Hospital for MRI and USS for fibroid evaluation. The data collected included their age, parity, and nationality. The StatsDirect software was used to analyze the fibroids according to the site, size, type, and number. Results: The findings of USS matched the MRI in the posterior fibroid sites in 52.5% of cases, followed by anterior (38.1%) and fundal (21.8%). For fibroid size, USS matched MRI findings in 83.3% for fibroids between >5 to ≤10 cm, 78.3% for fibroids between >2 to ≤5 cm, and 36.8% for fibroids sized ≤2 cm. Fibroids more than 10 cm in size were in agreement for 33.33% of fibroids. Submucosal fibroids matched in just 29.4% of cases, but for the subserosal fibroids, it was 44.8%. The matching score for more than four fibroids was 61.8%, followed by single fibroids (54.8%) and two fibroids (34.8%). Conclusions: Results of USS and MRI were reasonably correlated in terms of fibroid location and size. USS diagnosis of posterior wall and fibroids of size less than 2 cm highly matched MRI diagnosis.
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