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Showing 12 results for You
Dr J. Salimi, F. Yourdkhani, K. Moosavi, Volume 4, Issue 2 (9-2006)
Abstract
ABSTRACT
Background: In recent years, the endovenous laser therapy (EVLT) has been
proposed to treat the incompetent greater saphenous veins (GSV) to increase
patient comfort,and to reduce cost as well as risk. EVLT causes vein wall
thickening, luminal contraction and vein fibrosis. The purpose of this article,
as the first report from Iran, is to review our experience and outline the early
results and complication of EVLT. Materials and Methods: 22 patients (13
females and 9 males, mean age: 40.6±11 years, range: 25-64) underwent EVLT of
incompetent GSV segments with 810-nm diode laser with an average energy of 89.2
J/cm (range, 50-123 J/cm). Success rate was defined as absence of reflux
throughout the entire treated segment on follow-up doppler ultrasound (DUS) and
clinical resolution of symptoms. Results: Short-term results in the EVLT
of 22 GSV indicate a 100% rate of closure. Self-limiting complication were
occurred in 18% of patients and included moderate ecchymosis and paresthesias in
3 (13.5%), and 1 (4.5%) patients, respectively. No major complications such as
deep vein thrombosis and pulmonary embolism were occurred. DUS demonstrated 21
(95%) and 19 (90.9%) occluded GSVs at 12 weeks, and 24 weeks respectively.
Conclusion: The early results of our experiences are excellent. EVLT of the
incompetent GSV with an 810 nm diode laser appears to be an extremely safe
technique. EVLT is a very effective and safe with best cosmetic results and rare
side effects.
Dr. S.m.j. Mortazavi, M.a. Mosleh-Shirazi, M.r. Maheri, H. Yousefnia, S. Zolghadri, A. Haji-Pour, Volume 5, Issue 3 (12-2007)
Abstract
Background: In megavoltage radiotherapy rooms, ordinary concrete is usually used due to its low construction costs, although higher density concrete are sometimes used, as well. The use of high-density concrete decreases the required thickness of the concrete barrier hence, its disadvantage is its high cost. In a nuclear reactor, neutron radiation is the most difficult to shield. A method for production of economic high-density concrete with appropriate engineering properties would be very useful. Materials and Methods: Galena (PbS) mineral was used to produce of a high-density concrete. Galena can be found in many parts of Iran. Two types of concrete mixes were produced. The water-to-concrete (w/c) ratios of the reference and galena concrete mixes were 0.53 and 0.25, respectively. To measure the gamma radiation attenuation of Galena concrete samples, they were exposed to a narrow beam of gamma rays emitted from a cobalt-60 therapy unit. Results: The Galena mineral used in this study had a density of 7400 kg/m3. The concrete samples had a density of 4800 kg/m3. The measured half value layer thickness of the Galena concrete samples for cobalt- 60 gamma rays was much less than that of ordinary concrete (2.6 cm compared to 6.0 cm). Furthermore, the galena concrete samples had significantly higher compressive strength (500 kg/cm2 compared to 300 kg/cm2). Conclusion: The Galena concrete samples made in our laboratories had showed good shielding/engineering properties in comparison with all samples made by using high-density materials other than depleted uranium. Based on the preliminary results, Galena concrete is maybe a suitable option where high-density concrete is required in megavoltage radiotherapy rooms as well as nuclear reactors.
A.r. Montazerabadi, M. Ahmadian, M.r. Vahed, N. Yousefi, A. Fatehizadeh, P. Borhani, A. Rajabizadeh, A.r. Binesh, A. Shakerizadeh, Dr. A.h. Mahvi, Volume 10, Issue 3 (12-2012)
Abstract
Background: Radon (222Rn) Measurement in the
residential environments is very important because of
its effecting on human health and causing cancer in
the respiratory system. 222Rn is individually
responsible for half of the natural radiation received
in humans and influences on human by breathing.
Hence, this study was undertaken to access the 222Rn
level in the dormitories of Kerman university of
medical science (southeast of Iran) to ensure its
safety level. Materials and Methods: In this study, for
measuring 222Rn level in seven dormitories of the
Kerman University of Medical Sciences, the Lucas cell
technique was used. This study was undertaken
during the winter because of the high concentration
of radon in this season due to closed building
ambience. Results: In this study, the highest
measured radon gas rate was 24.5 Bq/m3 in Boustan
(1). Average concentrations of the radon gas in all
dormitories were 4.7 Bq/m3, which is lower than the
standard level. Conclusion: The results of this study
showed that the 222Rn level in all dormitories was
lower than the normal amount (48 Bq/m3) as well as
the standard level. Iran. J. Radiat. Res., 2012
10 (3‐4): 171‐175
M. Najafi, Dr. Mohammad Reza Deevband, A.a. Yousefi Diba, A. Amin Moghaddam, Volume 13, Issue 4 (10-2015)
Abstract
Background: Radiation therapy uses high-energy radiation to kill cancer cells. Photoneutron contamination and induced radioactivity of high energy therapeutic photon beams are considered as the main source of occupational exposure to radiation therapists who works with linear accelerators operating above 10 MV. Materials and Methods: The gamma dose rates were measured after termination of different treatment approaches using 15 MV photons and room entry times for each approach was determined. Based on the results of this study, the annual dose of radiation therapists was estimated. Results: The highest dose rate that measured in the treatment room was belonged to 3-field pelvic approach which was equal to 5 ± 1.1 µSv/h. The radiation therapist's room entry times were determined between 3 to 10 minutes and the annual dose was estimated up to 5.9 mSv/y. Conclusion: Although the estimated annual dose is less than the internationally permitted value, the undesirable dose to radiation workers could be reduced through considering recommended room entry times.
C.g. Lee, J. Lee, S. Kim, Dr. S.h. You, Volume 16, Issue 2 (4-2018)
Abstract
Background: This study was designed to suggest the possibility of hormone-related derangement in salvage radiotherapy (SRT) after radical prostatectomy in terms of prostate-specific antigen (PSA) control. Materials and Methods: Among 160 consecutive prostate cancer patients who received radical prostatectomy, 34 with SRT between 2004 and 2012 were retrospectively reviewed. The numbers of patients with pathologic T3-T4 stage, Gleason score 8-10, and positive resection margin were 11 (32.4%), 10 (29.4%), and 17 (50.0%), respectively. Median SRT dose was 64.8 Gy (range, 52.9-70.0 Gy) with 1.8-2.3 Gy fractionations. Biochemical failure-free survival after SRT was counted and the median follow-up period was 32.5 months (range, 10-118 months). Results: After SRT, the median time for PSA to decrease to less than 0.2 ng/mL was four months (range, 0-25 months). The three-year survival rate was 60.3%. On univariate analysis, preferential hormone therapy (PHT) (p=0.022), higher PSA at SRT (p=0.005), and higher PSA after surgery (p=0.003) were related to a shorter biochemical survival period. On multivariate analysis, lower PSA at SRT (p=0.016), higher radiation dose (p=0.007), and non-PHT (p=0.046) suggested a consistent PSA control. Conclusion: According to these results, low PSA values by hormonal intervention need to be reconsidered with a different way to look at the relationship between the PSA and hormone therapy. SRT should be considered for postoperative salvage treatment regardless of the hormone-related PSA values.
A. Rabiei, M. Shamsaei, Dr. H. Yousefnia, A.r. Jalilian, Volume 16, Issue 4 (10-2018)
Abstract
Background: In this study, human absorbed dose of a newly introduced bone imaging agent, 68Ga-(4-{[(bis(phosphonomethyl))carbamoyl]methyl}-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (68Ga-BPAMD), was estimated based on the rats data. Materials and Methods: 68Ga was obtained from the 68Ge/68Ga generator and it's radionuclidic and radiochemical purities were investigated. 68Ga-BPAMD complex was prepared at optimal conditions and the radiochemical purity was studied using instant thin layer chromatography (ITLC) method. The final preparation was injected to the normal rats and the biodistribution of the complex was followed up to 120 min post injection. The accumulated activity for animal organs was calculated. Finally, the human absorbed dose of the complexes was estimated by RADAR method. Results: 68Ga-BPAMD complex was prepared in high radiochemical purity (>99%, ITLC) at optimal conditions. The biodistribution of the complex demonstrated that the main remained radioactivity would considerably accumulate into the bones. The results showed the highest amounts of absorbed dose on the bone surface (0.253 mGy/MBq) and in the bone marrow (0.250 mGy/MBq), while the other organs would receive an insignificant absorbed dose after injection of the 68Ga-BPAMD complex. Conclusion: The comparison of dosimetric results for 68Ga-BPAMD with other complexes shows this complex is a safer agent for bone scanning. This property as well as other characteristics such as the high resolution images of the positron emission tomography (PET) scanning and the availability of 68Ga in the form of 68Ge/68Ga generator, make this complex as a suitable agent for PET bone imaging.
M.h. El Batanouny, Dr. R.m. Yousri, S. Mahfouz, E.s. Salem, Volume 17, Issue 1 (1-2019)
Abstract
Background: Exposure to ionizing radiation is inevitable. Using of low-level laser therapy (LLLT) stimulates tissue repair and reduces inflammation. The objective of the present study aimed at evaluating the therapeutic efficacy of Helium-Neon (He-Ne) laser in stimulating the reparative processes in the liver of mice after whole body gamma-irradiation (WBγ-I). Materials and Methods: Two hundred and sixty four female mice were divided into 6 groups: Control, Laser irradiated, One shot gamma irradiated group, One shot + laser irradiated, Cumulative gamma irradiated and Cumulative + laser irradiated. Ionizing radiation was performed using a Cesium-137 source. Two modes of exposure were used, 1- Mice were irradiated with a single shot sublethal dose of 5 Gy. 2- The same dose was given in fractionated mode daily installations of 1 Gy. Laser treatment was carried out using a computerized scanner emitting He-Ne (CW). The assessment of serum transferases (AST & ALT) was performed along with histopathological (HP) assessment of liver biopsies. Results: There was a significant increase in serum transaminases above the control levels in gamma irradiated groups. Laser therapy of these groups was accompanied by a significant decrease in the elevated levels of transaminases. HP changes in the liver of the shot gamma-irradiated group showed that the main brunt of damage was on the liver cells. Meanwhile, in the cumulative gamma-irradiated group the main brunt was on the vascular system including the central veins and the portal blood vessels. Conclusion: It could be concluded that mice exposed to WBγ-I suffered from aggravated HP changes in the liver tissues accompanied by disturbances in the level of liver enzymes. These undesirable alterations were ameliorated by the treatment of the experimental mice by He-Ne laser before being irreversibly damaged.
E.h. El-Araby, Ph.d., D.h. Shabaan, Z. Yousef, Volume 19, Issue 3 (7-2021)
Abstract
Background: The presence of radon and radioactive nuclei emitted from uranium could result in a radiological hazard. Humans are exposed to natural radiation, which arises from cosmic radiation, radon gas, and radiation from radioactive nuclei of each thorium, uranium, and thorium. Methods and Methods: This research cares to study the concentration of the natural radioactivity (238-U, 232-Th and 40-K) and radon for fourteen samples of soil from different fourteen location in Wadi Hodein region in Egypt (Southern Eastern Desert). The radon gas was measured using CR-39 detector, while the activity concentration for natural radioactivity measured by HPGD system. Results: The results of the gamma ray spectroscopy show that main activity concentration of 238-U, 232-Th and 40-K are 13.04±1.15, 12.33±1.54 and 445.33±23.54 Bq/Kg respectively. The 43% form concentration value for K-40 are higher than the exemption level 412 Bq/Kg proposed by the UNSCEAR 2008. Moreover, the 15% of values for absorbed dose Dab were higher than public average 57 nGy/h. But annul effective dose values AED were less than recommended limits for the radiation which reported by UNSCEAR 2000 and 2008. The mean value concentration of radon was 265.96± 25.45 Bq/m3. The results of samples show that 28.27% of the radon gas concentrations and annul effective dose from radon (AEDR) in soil is higher than allowed limit recommended from International Commission on Radiological Protection agency (ICRP 2007). Conclusions: Radium, shows good relationship with radon exhalation rate in soil. Good correlation observed between lung cancer per year per million people and radon concentrations for all soil samples.
F. Habibi, R. Faghihi, S. Zolghadri, Ph.d., H. Yousefnia, S. Sina, F. I Mohammadpour-Ghaz, Volume 20, Issue 1 (1-2022)
Abstract
Background: In recent years, Gallium-68 citrate has become known as an alternative radioisotope in nuclear medicine. As for its influences, 68Ga-based tracers have already been proposed as agents for positron emission tomography. In this research, the values of human absorbed dose for 68Ga-citrate and 67Ga-citrate were estimated using the medical internal radiation dose method based on biodistribution data in rats. Materials and Methods: 68Ga/67Ga-citrate was prepared from eluted 68Ga/67Ga-Cl3 and sodium citrate under multiple reaction forms. The biodistribution of 68Ga/67Ga–citrate radiolabeled compounds was investigated by dissection of five male rats at specific times after injection. The organs of the rats were removed and counted. Percentage of injected dose per gram was determined for each rat organ and the human absorbed dose was extrapolated using the rats’ data. Results: The results of estimating the human absorbed dose illustrate that 68Ga-citrate caused a much lower human absorbed dose compared with 67Ga-citrate. Conclusion: According to the results, it may be concluded that 68Ga-citrate, despite the better quality of PET imaging, is much safer in terms of absorption dose compared with 67Ga-citrate, and from this point of view, it is a more appropriate agent for imaging applications.
Mb B. Al Omran Al Omran, A. Mohamed Mehad Mohamed Mehad, S. Matoi, S.m. Abdul Qadir, A. Peluola, R. O’sullivan, N. Dayoub, Volume 20, Issue 4 (10-2022)
Abstract
Background: This study was designed to evaluate the matching percentage among findings of the ultrasound scans (USS) to the magnetic resonance imaging (MRI) in women with fibroids. Materials and Methods: This descriptive, retrospective study was conducted from January 2016 to December 2018. This study includes 205 female patients referred from the Gynaecological Department to the Radiological Department in the Bahrain Defense Force Hospital for MRI and USS for fibroid evaluation. The data collected included their age, parity, and nationality. The StatsDirect software was used to analyze the fibroids according to the site, size, type, and number. Results: The findings of USS matched the MRI in the posterior fibroid sites in 52.5% of cases, followed by anterior (38.1%) and fundal (21.8%). For fibroid size, USS matched MRI findings in 83.3% for fibroids between >5 to ≤10 cm, 78.3% for fibroids between >2 to ≤5 cm, and 36.8% for fibroids sized ≤2 cm. Fibroids more than 10 cm in size were in agreement for 33.33% of fibroids. Submucosal fibroids matched in just 29.4% of cases, but for the subserosal fibroids, it was 44.8%. The matching score for more than four fibroids was 61.8%, followed by single fibroids (54.8%) and two fibroids (34.8%). Conclusions: Results of USS and MRI were reasonably correlated in terms of fibroid location and size. USS diagnosis of posterior wall and fibroids of size less than 2 cm highly matched MRI diagnosis.
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