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Showing 5 results for Computed Tomography Angiography
Dr. A. Chaparian, H. Karimi Zarchi, Volume 16, Issue 1 (1-2018)
Abstract
Background: Computed tomography angiography (CTA) scan is a suitable imaging technique to evaluate the blood vessels. However, one major disadvantage is the potential risk of cancer related to ionizing radiation exposure during the procedures. The aim of this investigation was to estimate the risk of exposure induced cancer death (REID) values for some common computed tomography angiography (CTA) scans. Materials and Methods: The scan parameters and patient gender and age were collected for a total of 251 patients undergoing CTA scans of the head (51), carotid (50), abdomen (50), thoracic (50) and the lower extremities (50). The effective diameter, scan length, effective tube current and the dose-length product (DLP) values were obtained for each patient. The organ doses and the effective dose were calculated by the ImpactDose program. The REID values were estimated for the different CTA scans by the calculated organ doses and corresponding age- and sex- specific risk factors. Results: The REID values for the CTA scans of head were 17±4 and 20±3 per million, carotid were 35±9 and 67±14 per million, the lower extremities were 60±26 and 64±24 per million, thoracic were 97±28 and 204±72 per million, and for abdomen were 101±25 and 194±72 per million, for males and females, respectively. Conclusion: The results of this investigation showed that CTA scans are associated with non-negligible risk of exposure induced cancer. A variation in radiation cancer risk as a function of age and gender of the patients was demonstrated and found that the younger female patients were at the highest risk.
Y. Han, T. Wang, L. Lin, C. Yu, R. Lv, Z. Liu, T. Zhang, Ph.d., L. Han, Volume 20, Issue 1 (1-2022)
Abstract
Background: To identify the best time-interval for dual-source coronary computed tomography angiography (CCTA) with bolus tracking automatic trigger technique. Materials and Methods: 120 patients were randomly divided into four groups (A, B, C and D), with 30 patients in each group. Monitoring was begun 10 seconds after injection, and the monitoring time-intervals for groups A, B, C and D were 1.14, 1.47, 2.00 and 3.00 seconds, respectively. CCTA acquisition was triggered as the monitored concentration in the region of interest (ROI) exceeded 100 HU. The monitoring times, CT and dose length product (DLP) values of the four groups were compared statistically. The quality of recorded CCTA images was evaluated objectively, and the image quality of blood vessel segments was accessed subjectively. Results: there were no statistically significant differences in objective evaluations between the four groups (P>0.05). Subjective evaluation results showed no statistically significant differences between groups A (1.879±0.042), B (1.876±0.043) and C (1.881±0.052). Group D showed the highest subjective score (2.923±0.069), which was significantly different from groups A, B, and C (P<0.01). The monitoring times for groups A, B, C and D were 4.78±2.37, 3.76±1.39, 2.77±0.99 and 2.38±0.64, respectively; and the DLP values were 4.13±2.22, 2.18±0.80, 1.50±0.51 and 1.48±0.43 mGy·cm, respectively. DLP increases with increased monitoring times. Conclusion: When performing dual-source CCTA, a monitoring time-interval of 2 seconds with trigger scanning technique is the best choice, since it effectively reduces the radiation dose while providing satisfactory images.
F. Wang, W. Liu, S. Zhao, M.d., W. Ye, Volume 21, Issue 2 (4-2023)
Abstract
Background: The Background: To explore the influence of centrifugal massage on reducing the incidence of compartment syndrome after contrast extravasation (CM) and reducing the tension. Materials and Methods: A total of 62 patients with iodine contrast agent extravasation who underwent CT angiography in our hospital from March 2020 to March 2022 were chosen and separated into observation group (OG, n=31) and control group (CG, n=31) following the nursing plan. Patients in the CG adopted external application of drugs, and patients in the OG received centrifugal massage. The occurrence and duration of swelling, the incidence of compartment syndrome after contrast extravasation, nursing satisfaction, patients’ symptoms, and psychological status were compared between both groups. Results: The swelling degree and duration and incidence of compartment syndrome after contrast extravasation in the OG were declined relative to the CG (P<0.05). After 24 and 48 hours of intervention, patients in the OG had elevated self-rating scales compared to the CG (P<0.05). The nursing satisfaction of patients in the OG was elevated compared to the CG (P<0.05). After intervention, the anxiety and depression scores of the OG was decreased compared to the CG (P<0.05). The effective rate of treatment in the OG was elevated compared to the CG (P>0.05). Conclusion: Centrifugal massage for patients with CT enhanced scanning can prevent the incidence of CM after contrast extravasation, reduce the damage of contrast agent to tissues, and improve nursing satisfaction.
L. Wang, G. Tian, H. Zhang, J. Chen, Z. Sun, F. Guo, M.d., J. Shen, Volume 22, Issue 3 (7-2024)
Abstract
Background: This study explores the predictive value of Computerized Tomography (CT) perfusion imaging, serum D-dimer (D-D), and serum matrix metalloproteinase-9 (MMP-9) levels for hemorrhagic transformation (HT) in patients with acute cerebral infarction post-thrombolysis. Materials and Methods: Patients with acute cerebral infarction who underwent thrombolytic therapy from February 2021 to February 2022 were included. CT perfusion imaging was conducted within a week post-operation. The study compared CT perfusion parameters and serum markers, analyzing differences and conducting univariate and multivariate analyses to explore their predictive value for HT. Results: No significant differences were found in hypertension, hyperlipidemia, stroke history, mean arterial pressure, fasting blood glucose, and platelet count pre-thrombolysis (P > 0.05). However, infarct diameter ≥ 5 cm and atrial fibrillation were more common in the study group, with higher pre-thrombolysis National Institutes of Health Stroke Scale (NIHSS) score, D-D, and MMP-9 levels (P < 0.05). CT perfusion showed lower relative cerebral blood volume (rCBV, relative cerebral blood flow (rCBF, and higher relative mean transit time (rMTT), relative time to peak (rTTP) in the study group (P < 0.05). D-D and MMP-9 levels were negatively correlated with rCBV, rCBF, and positively with rTTP, CTP integration index (P < 0.05). Conclusion: CT perfusion imaging, serum D-D, and MMP-9 levels are effective predictors of hemorrhagic transformation in acute cerebral infarction patients post-thrombolysis. These findings are valuable for guiding clinical treatment and monitoring.
H. Liu, Z. Zhao, H. Xu, W. Chen, Q. Lu, Ph.d., X. Chen, Volume 22, Issue 4 (10-2024)
Abstract
Background: To investigate the diagnostic value of head and neck computed tomography angiography (CTA) in combination with color Doppler ultrasonography (CDUS) in carotid artery stenosis in ischemic stroke (IS) patients. Materials and Methods: DSA examination was performed on all patients, and they were separated into mild group, moderate group, as well as severe group (n=30) according to the degree of vascular stenosis. Head and neck CTA and CDUS were used to examine the plaque length, thickness, and quantity of each group. The total plaque area, carotid intima-media thickness (IMT), common carotid artery index (CCA), internal carotid artery index (ICA) as well as vertebral artery index (VA) were compared. Results: A total of 110 narrow blood vessels were detected by CTA combined with ultrasound, and had a higher accuracy rate. The total plaque area, length, thickness and number of plaques, the values of CCA, ICA and VA, and IMT in the moderate together with severe groups presented higher relative to the mild group, and those in severe group presented elevated relative to the moderate group (P < 0.05). The sensitivity, specificity and accuracy of the combined detection of head and neck CTA and CDUS in the diagnosis of vascular stenosis in IS patients were higher relative to the single detection (P < 0.05). Conclusion: Head and neck CT angiography in combination with CDUS has a high application value in detecting carotid artery stenosis in IS patients, and provides an important reference value for the formulation of the next treatment plan and the assessment of patient prognosis.
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