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Showing 4 results for Indicator
Dr. P.k. Manigandan,
Volume 7, Issue 2 (9-2009)
Abstract
Background: A field study on the transfer of primordial radionuclides 238U, 232Th, 40K and fallout radionuclides 210Po in different plant species in tropical forest of western Ghats environment is presented. Material and Methods: The Top storey, Second storey, Shrubs and epiphytic plant species were chosen and concentration of these radionuclides in plant and soil were measured by employing gamma ray spectrometer and alpha counter. Results: The concentration ratio shows the variation in different species while a wild plant Elaeocarpus oblongus and epiphytic plants indicated preferential uptake of these radionuclides. Conclusion: The dust trapped in the root system of epiphytic plants could be used as bioindicator to monitor fallout radionuclides in the Western Ghats. The concentration of 232Th and 40K in leaves depends on the age of the leaves. Iran. J. Radiat. Res., 2009 7 (2): 85-90
C.r. Rathi, E.m. Ross, S.g. Wesley,
Volume 9, Issue 1 (6-2011)
Abstract
Background: Due to the presence of radioactive
minerals such as monazite, the beach sand of the
west coast of Kanyakumari exhibits high natural
background radiation. Hair is a good indicator of
radionuclides in the human body. An attempt is
taken to measure the 210Po activity in human hair
samples and the factors affecting it. Material and
Methods: 210Po activity was analysed in 47 individuals
including males and females living in Kanyakumari
district, Tamil Nadu, India. The activities were
measured using a Nucleonix® Radiation Counting
System (RC 605A). Results: The activity was in the
range of 9.89 ± 4.43 to 58.85 ± 6.27 milli Becquerel
per gram. 210Po activity was observed in the hair
samples when compared to the global values were
comparatively higher. Conclusion: Hair samples
obtained from the users of home-made and medicinal
oil had higher concentration of 210Po compared to
that of people using branded oils. These high values
may be attributed to the hair oil usage and this is a
topic of interest for future studies. Iran. J. Radiat. Res.,
2011 9(1): 41-47
Ph.d., H. Mozdarani, R. Rahbar Parvaneh, S. Mozdarani, M. Lashkari,
Volume 20, Issue 2 (4-2022)
Abstract
Background: There is not yet an appropriate biomarker to predict or follow radiosensitivity of Breast cancer (BC) patients during or after radiotherapy. The aim of this study was to monitor chromosomal aberrations (CA) induced before and during radiotherapy in peripheral blood lymphocytes of BC patients. Materials and Methods: Age-matched twenty normal healthy individuals and 20 invasive ductal BC patients were enrolled in this study. A blood sample was obtained from normal healthy women and BC patients before and after the first, two and four weeks after radiotherapy. Lymphocyte microculture was initiated in 4.5ml complete RPMI-1640 medium. Cells were harvested 50 hours after culture initiation. Cells were harvested based on standard protocols. Hundreds of well-spread mitoses were scored under a light microscope with a magnification of x1000 for various types of CA. Data were statistically analyzed and p<0.05 was considered a significant difference. Results: Results indicated a higher frequency of CA in lymphocytes of un-irradiated BC patients compared to healthy normal individuals, although not statistically significant (p>0.05). High frequencies of CA were observed in lymphocytes of BC patients after radiotherapy, significantly different from the un-irradiated group (p<0.01). The increase in the frequency of CA was increased with increasing radiation dose. Conclusion: Genome instability may contribute to high background and radiation-induced CA in lymphocytes of BC patients. However, there is also the possibility of a radio-adaptation of cells during the course of radiotherapy. Results imply that dicentric chromosomes might be valuable cytogenetic bioindicators to monitor the response of BC patients to radiotherapy.
Y. Li, J. Liu, J. Zhou, B.m. L. Zhang, M.d., X. Li,
Volume 21, Issue 3 (7-2023)
Abstract
Background: We aimed to analyze the value of volume rendering (VR) in diagnosing different solitary pulmonary nodules (SPNs) with diameter less than 1.0 cm and assessing invasion depth in lung adenocarcinoma. Materials and Methods: In total, 908 patients with SPN that was confirmed by postoperative pathology were included, followed by an analysis of the imaging characteristics (including microvascular sign, vascular convergence, lobulation, and spiculation) of malignant and benign SPN based on VR. Moreover, the detection rates of imaging signs of three types of malignant SPNs (pure ground grass nodule, pGGN; part-solid nodule; and solid nodule) classified by SPN density and three invasion depths of adenocarcinoma (pre-invasion lesion, PIL; micro invasive adenocarcinoma, MIA; and invasive adenocarcinoma, IAC) were also analyzed. Results: The microvascular sign detection rate was higher while vascular convergence and spiculation detection rates were lower in malignant SPN than in benign SPN. The microvascular sign possessed high sensitivity (82%) and specificity (72%) in predicting malignant and benign SPNs. The microvascular sign detection rate decreased while vascular convergence, lobulation, and spiculation detection increased with the rising density of malignant SPN. Furthermore, the detection rates of the four imaging signs all increased with the adenocarcinoma invasion depth. Microvascular sign showed good detecting ability in low density SPNs pGGN (81.8%), part-solid nodules (95.8%), and in all three invasion depths of adenocarcinoma (PIL [68.2%], MIS [95.3%], and IAC [87.2%]). Conclusion: These imaging features distinguished by VR exhibited an excellent differential diagnostic ability of various SPNs as well as invasion depth of lung adenocarcinoma.
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