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Showing 2 results for Positron Emission Tomography Computed Tomography
P. Zhao, Y. Xu, Ph.d., C. Xie, M. Zhan, Y. Qian, Z. Gao,
Volume 22, Issue 1 (1-2024)
Abstract
Background: A meta-analysis of the effectiveness of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography Computed Tomography (PETCT) in assessing the effects of neoadjuvant chemotherapy (nCRT) for Rectal cancer (RC) was performed to provide a reference for better clinical assessment in the future. Materials and Methods: Relevant literature on the assessment of the effects of MRI and PETCT on RC nCRT was screened through PubMed, Cochrane, EMBAS and other literature databases, and the final literature for analysis was determined after cross-screening by two study team members. Review Manager 5.3 software was used to assess the quality of the literature and extract relevant information such as authors, year of publication, and results, and meta-analysis was performed using Stata 15.1 software. Results: Through screening, six references were finally included, totaling 396 cases of study subjects, and the results of literature quality evaluation showed that the selected literature was of high quality and had some reference value. Meta-analysis revealed a sensitivity of 0.76 and a specificity of 0.74 for the final combination of MRI; the sensitivity and specificity of the final combined PETCT were 0.78 and 0.71, respectively. Deek’s test showed P>0.05 for both MRI and PETCT, with no publication bias. Conclusion: MRI and PETCT are similarly effective in predicting the effect of RC nCRT.
Y.m. Chi, Dr. C.c. Chang,
Volume 22, Issue 4 (10-2024)
Abstract
Positron emission tomography/computed tomography (PET/CT) with radioactive Fluorine-18 fluorodeoxyglucose (FDG) is a highly sensitive tool that is used for detecting malignancy. However, it can sometimes produce false positive results if done after vaccination. To prove this, we present two cases of individuals who received pneumococcal polysaccharide vaccination (PPV) and later showed FDG accumulation in the axillary lymph nodes during PET/CT scans. The first case involves a 69-year-old man who underwent a PET/CT scan for a health checkup. The scan revealed low-grade FDG uptake in the left axillary lymph nodes. A thorough examination of his medical history revealed that the patient had received PPV in his left upper arm eight days prior to the checkup. The vaccination was suspected to have caused left axillary lymphadenopathy. The second case involves a 66-year-old woman who also underwent a PET/CT scan for a health checkup. The scan showed FDG-avid lymph nodes in the left axillary region and increased FDG uptake in the spleen. After further questioning, it was discovered that the patient had received PPV in her left upper arm eight days prior to the checkup. Seven days after the PET/CT scan, when a complete blood count with differential was performed on the second case, it revealed that all data were within normal limits. Further, an abdominal ultrasound was conducted, which showed normal findings in the spleen. Based on these results, the medical team concluded that the prior vaccination was the cause of the observed benign findings and emphasized the importance of carefully reviewing patient history to differentiate between benign findings and malignant lesions.
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