TY - JOUR JF - Int-J-Radiat-Res JO - Int J Radiat Res VL - 19 IS - 1 PY - 2021 Y1 - 2021/1/01 TI - Management of bulky high-grade pleomorphic sarcoma using grid therapy technique TT - N2 - In the present study, a case was reported concerning a patient with a bulky extremity soft tissue sarcoma treated with spatially fractionated Grid therapy and then followed by standard external beam radiotherapy. Treatment was performed using a Grid block to deliver 15 Gy in one fraction. There was one week interval break before EBRT treatment with 50 Gy in 25 fractions for the neoadjuvant external beam radiotherapy. The surgery was performed 4 weeks after the completion of radiotherapy. The follow-up time was considered as 24 months. The patient's general condition was good during this period without the presence of tumor recurrence or grade 3 or 4 treatment-related toxicities. Combining different treatment techniques like grid therapy is feasible and may improve the outcomes in the management of bulky high-grade soft-tissue sarcomas of the extremities. SP - 239 EP - 242 AU - Tajiki, S. AU - Gholami, S. AU - Kazemian, A. AU - Haddad, P. AU - Esfahani, M. AU - Ghalehtaki, R. AU - Rastjoo, A. AU - Pakniyat, F. AU - Meigooni, A.S. AD - Radiation Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran KW - Sarcoma KW - radiotherapy KW - Grid therapy. UR - http://ijrr.com/article-1-3486-en.html DO - 10.29252/ijrr.19.1.239 ER -