International Journal of Radiation Research
نشریه پرتو پژوه
Int J Radiat Res
Basic Sciences
http://ijrr.com
79
journal79
2322-3243
2345-4229
10.61186/ijrr
en
jalali
1396
10
1
gregorian
2018
1
1
16
1
online
1
fulltext
en
Evaluation of low dose diagnostic X-rays induced effect on the white blood cells count in Guinea pigs
Radiation Biology
Radiation Biology
مطالعه موردي
Case Report
<div style="text-align: justify;">Background: Exposure to ionizing radiation is known to have various effects on hematological parameters of biological sample. This study was aimed at evaluating the effect of ionizing radiation on some hematological parameters in guinea pigs. Materials and Methods: Thirty-six (36) apparently healthy adult guinea pigs of both sexes weighing between 700g – 1200g were used in the present study. The guinea pigs were categorized into three groups, 12 per group; group A (control), group B, and C were exposed to X-rays within the diagnostic range, using 70 kV and 12.5mAs; using X-ray machine MS-185, serial no. 0904 GE at a source to skin distance (SSD) of 90cm. Blood samples were collected from all the guinea pigs at intervals of 1 hour, 24 hours 72 hours, 168 hours and 336 hours post-irradiation, and subjected to standard hematological analysis. Results: A continuous decline in the mean total white blood cell count and mean lymphocyte, monocyte, neutrophil and eosinophil count after 1hour in both groups was observed, and more pronounced after 24 hours post-irradiation. However, stability was observed 72 hours post-irradiation in both groups. Conclusion: This study found a depleting effect of low dose ionizing radiation on white blood cell count, with appreciable recovery occurring after 72 hours onward. </div>
White blood cells, irradiation, Guinea pigs, ionizing radiation, hematological parameters.
129
132
http://ijrr.com/browse.php?a_code=A-10-1-711&slc_lang=en&sid=1
G.
Luntsi
geostuffy@unimaid.edu.ng
7900319475328460015637
7900319475328460015637
Yes
Department of Medical Radiography, College of Medical Sciences, University of Maidugri, Borno State, North-eastern Nigeria
V.S.
Daniel
7900319475328460015638
7900319475328460015638
No
Department of Medical Radiography, College of Medical Sciences, University of Maidugri, Borno State, North-eastern Nigeria
B.T.
Paul
7900319475328460015639
7900319475328460015639
No
Veterinary Teaching Hospital, University of Maiduguri, Borno State, North-eastern Nigeria
I.C.
Nwobi
7900319475328460015640
7900319475328460015640
No
Department of Medical Radiography, College of Medical Sciences, University of Maidugri, Borno State, North-eastern Nigeria
A.M.
Abdullahi
7900319475328460015641
7900319475328460015641
No
Veterinary Teaching Hospital, University of Maiduguri, Borno State, North-eastern Nigeria
M.S.
Ahmadu
7900319475328460015642
7900319475328460015642
No
Department of Radiology, University of Maiduguri Teaching Hospital, Borno State, North-eastern Nigeria
A.D.
Obotiba
7900319475328460015643
7900319475328460015643
No
Department of Medical Radiography, College of Medical Sciences, University of Maidugri, Borno State, North-eastern Nigeria
F.B.
Nkubli
7900319475328460015644
7900319475328460015644
No
Department of Medical Radiography, College of Medical Sciences, University of Maidugri, Borno State, North-eastern Nigeria