International Journal of Radiation Research
نشریه پرتو پژوه
Int J Radiat Res
Basic Sciences
http://ijrr.com
79
journal79
2322-3243
2345-4229
10.61186/ijrr
en
jalali
1387
6
1
gregorian
2008
9
1
6
2
online
1
fulltext
en
A survey on stimulatory effects of topical application of radioactive lantern mantle powder on wound healing
Radiation Biology
Radiation Biology
تحقيق بديع
Original Research
<span style="font-weight: bold">
Background: </span>Poorly educated people in some
parts of Iran use burned mantles as a wound
healing medicine. <span style="font-weight: bold">Materials and Methods: </span>To
perform surface area measurement, twenty rats
were divided randomly into two groups of 10
animals each. The first group received topical
burned radioactive lantern mantle powder on the
first to third days after making excision wounds. The
second group received non-radioactive lantern
mantle powder. For histological study, 36 male rats
were randomly divided into two groups of 18
animals each. Full thickness excision wound
(314±31.4 mm2) was made on the dorsal neck in all
animals after inducing general anesthesia. For the
first three days, cases had received topical
application of the radioactive lantern mantle
powder. Finally, to measure the tensile strength, an
incision was made on the dorsal neck of the rats.<span style="font-weight: bold">
Results:</span> Surface area measurement of the wounds
showed a progressive surface reduction in both
groups. Histological study showed a significant
statistically difference between cases and controls
with respect to fibrinoid necrosis and neutrophilic
exudate on days 3 and 14. Considering the
existence of granulated tissue, a significant
difference was observed between case and control
groups on days 3 and 7. Tensile strength study
showed no significant difference between the cases
and controls. <span style="font-weight: bold">Conclusion:</span> Topical use of radioactive
mantle powder can accelerate the healing process
of the wound in rats.
Lantern mantle, wound healing, radioactive, thorium.
97
102
http://ijrr.com/browse.php?a_code=A-10-1-279&slc_lang=en&sid=1
S.M.J.
Mortazavi
mmortazavi@sums.ac.ir
790031947532846001121
790031947532846001121
Yes
M.R.
Rahmani
790031947532846001122
790031947532846001122
No
A.
Rahnama
790031947532846001123
790031947532846001123
No
A.
Saeed-Pour
790031947532846001124
790031947532846001124
No
E.
Nouri
790031947532846001125
790031947532846001125
No
N.
Hosseini
790031947532846001126
790031947532846001126
No
M.M.
Aghaiee
790031947532846001127
790031947532846001127
No