International Journal of Radiation Research

en Significance of magnetic resonance zoomed imaging with parallel transmission intravoxel incoherent motion imaging, ultrasonography and dual-energy computed tomography imaging in the differential diagnosis of benign thyroid nodule and papillary thyroid carcinoma Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: To assess the use of computed tomography (CT), ultrasonography and magnetic resonance imaging (MRI) in distinguishing papillary thyroid cancer (PTC) from benign thyroid nodules. Materials and Methods: A total of 45 cases with benign thyroid nodules and 75 cases with papillary thyroid cancer were included from our hospital from March 2020 to December 2021. All patients were examined by MRI, ultrasonography and dual-energy CT. The outcomes of the two groups' MRI, CT and ultrasonography scans were compared. Results: The benign nodule group had significantly higher pure diffusion coefficient (D) (1.38±0.32 vs 0.95±0.12), perfusion fraction (F) values (17.13±4.35 vs 12.83±2.93) and iodine concentration (IC) plain scan scores (0.96±0.44 vs 0.56±0.37), whereas it had lower IC artery scores (2.65±1.11 vs 3.92±1.22) than those of the PTC group (p<0.001 for all). The Emax value of the PTC group was substantially greater than that of the benign nodule group (62.53±37.93 vs 25.37±8.38, p<0.001), and the percentage of nodules with aspect ratio ≥ 1 was higher in the PTC group than in the benign nodule group (48.0% vs 22.2%, p=0.005). The area under the curve (AUC) for MRI in the diagnosis of PTC patients was 0.885, which was substantially higher than those for ultrasonography (AUC=0.705) and CT exams (AUC=0.753) (p<0.001). Conclusion: MRI, ultrasonography and CT examinations are essential for discriminating between benign thyroid nodules and PTC. MRI has better diagnostic accuracy than the other two tests.</div> Papillary thyroid carcinoma, benign thyroid nodules, ZOOMit IVIM imaging, ultrasonography, dual-energy CT imaging. 537 543 http://ijrr.com/browse.php?a_code=A-10-1-1077&slc_lang=en&sid=1 Y. He yongshenghe1431@163.com 7900319475328460024412 7900319475328460024412 Yes Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China X. Qi 7900319475328460024413 7900319475328460024413 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China X. Luo 7900319475328460024414 7900319475328460024414 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China W. Wang 7900319475328460024415 7900319475328460024415 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China H. Yang 7900319475328460024416 7900319475328460024416 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China M. Xu 7900319475328460024417 7900319475328460024417 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China X. Wu 7900319475328460024418 7900319475328460024418 No Department of Radiology, Ma’anshan People's Hospital, Maanshan, Anhui, 243000, China W. Fan 7900319475328460024419 7900319475328460024419 No School of graduate, Wan’nan Medical College, Wuhu, 241000, China