International Journal of Radiation Research

en Computed tomography guided nerve interventional therapy in ischemic cerebrovascular disease Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: To explore the impact of head and neck computed tomography (CT) guided nerve interventional therapy in ischemic cerebrovascular disease (ICVD) patients. Materials and Methods: Patients with ICVD (n=100) admitted to our hospital from December 2021 to December 2022 were selected and randomly allocated into control group (CG) and observation group (OG). The CG received drug treatment, and the OG drug treatment before surgery and treated with head and neck CT combined with nerve intervention therapy. Interventional therapy was conducted via endovascular stenting. The National Institute Health of Stroke Scale (NIHSS) score, activities of daily living (ADL) score, vascular recanalization rate, blood flow of the diseased vessels along with occurrence of adverse reactions in both groups were compared. Results: After therapy, NIHSS score in both groups was declined, and lower in the OG relative to the CG (P<0.05), while ADL score in both groups was elevated, and higher in the OG relative to the CG (P<0.05). The vascular recirculation rate of the OG was 86.00%, higher relative to 60.00% in the CG (P<0.05). Vs (peak systolic flow velocity) and Vd (end diastolic flow velocity) in both groups was lessened post treatment, and lower in the OG relative to the CG (P<0.05). The occurrence of adverse reactions in two groups showed no significant difference (P>0.05). Conclusion: CT guided nerve interventional therapy was effective for the treatment of ICVD patients, which promoted vascular recanalization and nerve function recovery, effectively improve vascular endothelial function and cerebral blood flow of patients, and improve patient life quality.</div> Cerebrovascular disease, computed tomography, hypoxia-ischemia, nerve interventional therapy, vascular recanalization. 707 711 http://ijrr.com/browse.php?a_code=A-10-1-1103&slc_lang=en&sid=1 Y. Quan 7900319475328460024946 7900319475328460024946 No Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China Y. Jin 7900319475328460024947 7900319475328460024947 No Division of Life Science Metrology, National Institute of Metrology, Beijing 100013, China Y. Liu 7900319475328460024948 7900319475328460024948 No Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China S. Hu 7900319475328460024949 7900319475328460024949 No Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China X. Yin 7900319475328460024950 7900319475328460024950 No Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China M. Jin 7900319475328460024951 7900319475328460024951 No Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China W. Jiang jiangweijian2018@163.com 7900319475328460024952 7900319475328460024952 Yes Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China