en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">This study aimed to investigate the impact of a comprehensive nursing plan on post-radiooperative respiratory function, quality of life (QoL), and self-care ability in patients with lung cancer (LC) undergoing radiotherapy and surgery. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A total of 100 LC patients undergoing radiotherapy and surgery were randomly assigned to either the Routine Nursing Care (RNC) group (n = 50) or the Comprehensive Nursing Care (CNC) group (n = 50). Various parameters, including respiratory function, visual analog scale (VAS), self-rating anxiety scale (SAS), self-rating depression scale (SDS), Pittsburgh sleep quality index (PSQI), exercise of self-care agency scale (ESCA), European Organization for Research and Treatment of Cancer (EORTC), and complication rate, were assessed. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Compared to the RNC group, the CNC group exhibited a significant decrease in respiratory frequency and an increase in oxygen saturation, maximal breathing capacity, minute ventilation volume, and forced expiratory volume in 1 s (FEV1) (P < 0.05). Additionally, CNC group scores for VAS, SAS, SDS, and PSQI were lower, while ESCA and EORTC scores were higher compared to the RNC group (P<0.05). Complication rates post-intervention was significantly lower in the CNC group (4.0%) compared to the RNC group (28.0%) (P < 0.05). </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">In conclusion, comprehensive nursing intervention effectively improves post-radiotherapy operative respiratory function, anxiety, depression, and sleep quality. Furthermore, it enhances self-care ability and QoL in patients with LC undergoing radiotherapy and surgery while reducing the incidence of complications. These findings support the clinical application of comprehensive nursing care in this patient population.</span></span></span></span></span></span></span></span></span></div> Comprehensive nursing, lung cancer, radiotherapy, respiratory function test, quality of life, self-care ability. 919 926 http://ijrr.com/browse.php?a_code=A-10-1-1258&slc_lang=en&sid=1 L. Ye 7900319475328460028604 7900319475328460028604 No Department of Respiratory Medicine, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China J. Huang 7900319475328460028605 7900319475328460028605 No Department of Nephrology, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China F. Qiu zhongshou4830010@163.com 7900319475328460028606 7900319475328460028606 Yes First Area Department of Pediatrics, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China