International Journal of Radiation Research

en Value of Multi-slice Spiral CT Combined with Tumor Markers in Diagnosing Benignity and Malignancy of Hepatic Tumors Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: multi-slice spiral computed tomography (MSCT) combined with tumor marker detection can distinguish the nature of hepatic tumors. Meanwhile, diagnosing hepatic tumors is crucial for improving the survival rates (SR) of patients. Materials and Methods: data from 98 patients with hepatic tumors who underwent radiological examinations and treated in our hospital from December 2022 to December 2023 were collected. Pathological reports were arranged for patients, and based on the results, patients were categorized into benign tumor and malignant tumor groups (BT and MT groups). Clinical information such as pathological results, gender, and medical history was recorded and compared. After MSCT examination, the imaging features of patients were documented, and tumor markers in serum were detected. The accuracy of tumor markers alone and combined examination in determining the nature of hepatic tumors was compared. Results: the positivity rate (PR) of MSCT combined with tumor markers in the MT group (89.02%) was higher to that in the BT group (64.44%). The accuracy of the combined diagnosis in judging hepatic tumor nature was 64.57%, with a sensitivity of 89.02% and specificity of 35.56%. The area Under Curve (AUC) of the combined examination was 0.813, being higher than that of MSCT or tumor marker diagnosis alone. Conclusion: MSCT combined with tumor markers exhibited remarkable clinical value in determining benign and malignant hepatic tumors, with improved diagnostic accuracy and sensitivity, enabling its widespread application in early screening of hepatic tumors.</div> Spiral cone-beam computed tomography, tumor biomarkers, liver neoplasms, diagnosis. 577 583 http://ijrr.com/browse.php?a_code=A-10-1-1370&slc_lang=en&sid=1 D. Zhang 7900319475328460031369 7900319475328460031369 No Graduate School, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China L. Tang 7900319475328460031370 7900319475328460031370 No Department of Radiology, 903th RD Hospital of PLA, Hangzhou, Zhejiang Province, China X. Long xiejiati922465041@163.com 7900319475328460031371 7900319475328460031371 Yes Department of Medical lmaging, Shanghai University Mengchao Cancer Hospital, Shanghai, China