International Journal of Radiation Research

en Influence of bolus materials on dose deposition in electron beam radiotherapy: A Monte Carlo simulation Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: This study employed Geant4 to evaluate the comparative effects of various bolus materials on dose deposition during electron beam radiotherapy. Materials and Methods: A bolus was simulated in Geant4, positioned 100 cm away from the accelerator source, with dimensions of 30 cm × 30 cm and varying thicknesses. The materials tested included water, glycerol, polystyrene, and silica gel. A tissue-equivalent phantom was positioned adjacent to the bolus, and voxels were incorporated to measure dose deposition as 6 and 9 MeV electron beams passed through it. The analysis focused on comparing maximum doses, effective therapeutic depths (ETDs), and dose distributions beyond the ETD. Results: The depth of maximum dose (dmax) showed a linear relationship with increasing bolus thickness, moving closer to the phantom surface with material-specific coefficients. The onset depth of the ETD decreased progressively until it reached the phantom surface. For equivalent bolus thicknesses where the ETD did not initial at the surface, the ETD regions exhibited similar dimensions, with onset depths in the order: silica gel < glycerol < water < polystyrene. When the ETD began at the surface, the size of the ETD regions followed the same order. The relative dose beyond the ETD generally followed the order: silica gel > water > glycerol > polystyrene. Conclusion: Bolus materials exert a significant influence on dose distribution in electron beam radiotherapy.</div> Monte Carlo method, elastomeric polymer, radiation dosage, electrons. 25 30 http://ijrr.com/browse.php?a_code=A-10-1-1450&slc_lang=en&sid=1 D. Kong 7900319475328460032754 7900319475328460032754 Yes Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China L. Hui 7900319475328460032755 7900319475328460032755 No Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China B. Yang 7900319475328460032756 7900319475328460032756 No Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China J. Huang 7900319475328460032757 7900319475328460032757 No Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China Y. Zhao 7900319475328460032758 7900319475328460032758 No Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China K. Gu 7900319475328460032759 7900319475328460032759 No Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, WUXI 214122, China