en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background:</span></span></span></span></span></span> <span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">Cutaneous Rosai-Dorfman disease (CRDD) is an uncommon histiocytic proliferative disorder localized to the skin, representing merely 3% of all reported cases of Rosai-Dorfman disease (RDD). Despite numerous investigations into the clinical and pathological attributes of CRDD, there are few works on its ultrasonic manifestations, with the majority of studies being limited to individual case reports. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Case presentation: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">This paper presents the case of a 66-year-old female who exhibited red nodules on the skin of her face, accompanied by pruritus, which persisted for 2 years and notably affected her quality of sleep. Clinical assessment substantiated a diagnosis of CRDD, and subsequent ultrasound imaging revealed a low-echo nodule. The nodule (2.4 cm by 0.4 cm) was identified within the skin of the right eyebrow and exhibited pronounced blood flow. Following multiple sessions of targeted treatment, there was a notable improvement in the lesion, and no recurrence was detected during subsequent follow-up evaluations. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Conclusion: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">This case exemplifies the typical ultrasound features associated with CRDD and underscores the limitations inherent in ultrasound diagnostics, thereby highlighting the vital importance of histopathological assessment.</span></span></span></span></span></span></span></span></span></span></div> Ultrasound, cutaneous Rosai-Dorfman disease, color Doppler. 293 295 http://ijrr.com/browse.php?a_code=A-10-1-1490&slc_lang=en&sid=1 Y. Qin 7900319475328460033040 7900319475328460033040 No Department of Ultrasound, Peking University Third Hospital, Beijing, China S-r. Liu 7900319475328460033041 7900319475328460033041 No Department of Ultrasound, Peking University Third Hospital, Beijing, China G-l. Wu 7900319475328460033042 7900319475328460033042 No Department of Ultrasound, People's Hospital of Rongcheng, Rongcheng, China L. Jiang 7900319475328460033043 7900319475328460033043 No Department of Ultrasound, Peking University Third Hospital, Beijing, China S. Tan 7900319475328460033044 7900319475328460033044 No Department of Ultrasound, Peking University Third Hospital, Beijing, China