[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 12, Issue 4 (10-2014) ::
Int J Radiat Res 2014, 12(4): 343-346 Back to browse issues page
Assessment of molybdenum breakthrough levels in molybdenum-99/technetium-99m generators: One year experience at NIMRA Jamshoro Pakistan
S.A. Memon, N.A. Laghari, S.T. Qureshi, F. Mehdi
Nuclear Institute of Medicine and Radiotherapy (NIMRA) Jamshoro, Pakistan , physicistsajjad@hotmail.com
Abstract:   (5805 Views)

Background: Technetium-99m radioisotope is the backbone of any nuclear medicine institute. This radioisotope is acquired by the elution of Molybdenum-99/Technetium-99m generator which emits 141 keV gamma ray and having 6.04 hour half-life. Occasionally the contents of Molybdenum-99 may mix up with elute, which may affect image quality and patients may receive higher doses than recommended. This study was initiated to check and evaluate the contamination of Molybdenum-99 in Molybdenum-99/Technetium-99m generators used at Nuclear Institute of Medicine and Radiotherapy (NIMRA) Jamshoro Pakistan before its administration to patients for diagnostic procedures. Materials and Methods: The Molybdenum-99 impurity in Technetium-99m elute for 50 generators was studied during the year 2012. The measurements were made using dose calibrator and a standard canister at the time of first elution of the generators. The dose calibrator displays result after executing various steps in a sequence. Due to some production process error or any mechanical fault high activity of Molybdenum-99 was recorded and removed with decrease in Technetium-99m yield. Results: The most of eluted generators (90%) contained 10% of molybdenum breakthrough of the permissible limit (P < 0.05). The high activity of Molybdenum-99 was recorded in only 6% of the generator and removed by using standard methods with some reduced Technetium-99m activity. Conclusion: The molybdenum breakthrough was according to recommended standards in most of the generators. The removal of high contents of Molybdenum-99 enabled the institute to continue routine imaging services by improved image quality and reduction in radiation dose to the patients.

Keywords: Dose calibrator, 99Mo-99mTc generator, 99Mo, molybdenum breakthrough, 99mTc
Full-Text [PDF 424 kb]   (8421 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Memon S, Laghari N, Qureshi S, Mehdi F. Assessment of molybdenum breakthrough levels in molybdenum-99/technetium-99m generators: One year experience at NIMRA Jamshoro Pakistan. Int J Radiat Res. 2014; 12 (4) :343-346
URL: http://ijrr.com/article-1-1353-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 12, Issue 4 (10-2014) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 4419