[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 17, Issue 3 (6-2019) ::
Int J Radiat Res 2019, 17(3): 485-491 Back to browse issues page
Evaluation of the effects of dental filling material artifacts on IMRT treatment planning in patient with nasopharyngeal cancer
P. Saadatmand, A. Shanei, A. Amouheidari, I. Abedi
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran , shanei@med.mui.ac.ir
Abstract:   (2433 Views)
Background: Presence of artifacts, caused by dental filling high-Z materials (DFM), on intensity-modulated radiation therapy (IMRT) treatment plan CT images may lead to uncertainty in head and neck calculated dose distributions. Hence, the purpose of this study was to investigate the effects of DFM on the IMRT calculated dose distribution and consequent radiobiological derived outcomes for nasopharyngeal cancer patients. Materials and Methods: IMRT optimization of two groups (15 patients in each) of nasopharyngeal cancer (NPC) patients with (group I) and without (group II) dental amalgam was performed by using the Prowess Panther treatment planning system (TPS). For all the patients, target prescribed dose was 70 Gy to planning target volume. We used 3 sets of treatment plans including; nine fields arrangement (F9E) and two plans of seven fields (namely: F7 and F7E) at different angles. The dose volume histograms (DVHs), monitor units (MUs), Homogeneity index (HI), conformity index (CI), Tumor control probability (TCP) and normal tissue complication probability (NTCP) of main organs at risk (OARs) were analyzed. Results: According to the results, the TCP of PTV70 due to presence of dental filling material was significantly decreased (p=0.031). On the other hand received dose by mandible, left cochlea, both eyes and right optic nerve were considerably different between patients with and without artifacts (p<0.05), whereas mandible showed the maximum differences (up to 315.65 cGy) compared to the other studied OARs. Conclusion: Results Presence of dental artifact in patients with nasopharyngeal carcinoma leads to uncertainty in calculated dose of IMRT treatment plans, especially for mandible as an OAR.
Keywords: Dental Filling Material, Treatment Planning, Intensity Modulated Radiation Therapy, Nasopharyngeal Carcinoma.
Full-Text [PDF 2069 kb]   (976 Downloads)    
Type of Study: Technical Note | Subject: Radiation Biology
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Saadatmand P, Shanei A, Amouheidari A, Abedi I. Evaluation of the effects of dental filling material artifacts on IMRT treatment planning in patient with nasopharyngeal cancer . Int J Radiat Res 2019; 17 (3) :485-491
URL: http://ijrr.com/article-1-2610-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 17, Issue 3 (6-2019) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.04 seconds with 32 queries by YEKTAWEB 4549