Safe chemotherapy and targeted therapy for
treating locally advanced NPC in a G6PD-deficient patient: case report and literature review
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Y.M Jiang , X.D. Zhu |
Department of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning530021, People's Republic of China , zhuxiaodonggxmu@163.com |
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Abstract: (2956 Views) |
The article was first report a case of a 32-year-old female with NPC that is G6PD-deficient. The patient completed induction chemotherapy and concomitant chemoradiotherapy successfully. The patient experienced grade 1 neutropenia , grade 1 diarrhea, and grade 2 acne-like skin reactions during the three cycles of induction chemotherapy. Grade 1 neutropenia, grade 1 diarrhea, grade 2 oral mucositis and grade 1 skin reactions were observed during the concomitant chemoradiotherapy. No hemolytic events were observed. We conclude that it is safe for G6PD-deficient patients with NPC to received chemotherapy and targeted therapy. |
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Keywords: nasopharyngeal carcinoma, G6PD deficiency, chemotherapy, cetuximab, radiotherapy. |
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Full-Text [PDF 1599 kb]
(2104 Downloads)
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Type of Study: Case Report |
Subject:
Radiation Biology
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