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:: Volume 18, Issue 3 (7-2020) ::
Int J Radiat Res 2020, 18(3): 599-604 Back to browse issues page
Volumetric-modulated arc stereotactic radiotherapy for intramedullary cervical spinal cord metastases: Report of two cases
Y. Mori , T. Mori, K. Adachi, S. Abe, Y. Oshima, A. Takeuchi, M. Ito
Department of Radiology and Radiation Oncology, Aichi Medical University, Nagakute, Aichi, Japan , yoshim@aichi-med-u.ac.jp
Abstract:   (1516 Views)
The treatment results of intensity-modulated stereotactic radiotherapy (IM-SRT) by volumetric-modulated arc therapy (VMAT) for intramedullary cervical spinal cord metastases (IMCSCM) in two cases were presented. Case 1: A 76-year-old woman showed left-sided motor weakness and left arm pain and dysesthesia due to IMCSCM at C [cervical] 6-7 (located a little to the left laterally) with multiple small brain metastases from thyroid carcinoma.  Multiple brain metastases were successfully treated by stereotactic radiosurgery (SRS). In addition, IMCSCM was treated by IM-SRT. Case 2: A 48-year-old man presented with asymptomatic IMCSCM at C2 (located a little to the right laterally) after conventional whole brain radiotherapy (WBRT) and multiple sessions of SRS/SRT for multiple brain metastases from lung adenocarcinoma. IMCSCM was treated by IM-SRT. In both cases 39 Gy in 13 fractions (without PTV [planning target volume] margin, D95%=95% dose) was delivered to the IMCSCM (0.3 ml and 0.5 ml in volume respectively) by coplanar 2-full circular arc VMAT. The maximum dose to the tumor was 46.3 Gy in case 1 and 47.1 Gy in case 2. IMCSCM in both cases shrank markedly without adverse effects during the follow-up period of 32 months and 8 months respectively. The symptoms of the extremities in case 1 were subsided completely until the patient’s death at 34 months after SRT from lung metastasis. In case 1 IMCSCM had been thought to be a relatively radioresistant thyroid carcinoma metastasis. In case 2 IMCSCM was near the field of the prior WBRT. However, both tumors were successfully treated without adverse effects by VMAT IM-SRT.
Keywords: Metastasis, spinal cord, intramedullary, cervical, volumetric-modulated arc therapy. 
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Type of Study: Case Report | Subject: Medical Physics
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Mori Y, Mori T, Adachi K, Abe S, Oshima Y, Takeuchi A et al . Volumetric-modulated arc stereotactic radiotherapy for intramedullary cervical spinal cord metastases: Report of two cases. Int J Radiat Res. 2020; 18 (3) :599-604
URL: http://ijrr.com/article-1-3096-en.html

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Volume 18, Issue 3 (7-2020) Back to browse issues page
International Journal of Radiation Research
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