:: Volume 5, Issue 4 (3-2008) ::
Int J Radiat Res 2008, 5(4): 153-168 Back to browse issues page
Historical review of interstitial prostate brachytherapy
S.B. Awan, M. Hussain, S.A. Dini, A.S. Meigooni
, alimeig@email.uky.edu
Abstract:   (17648 Views)
In the recent years, interstitial brachytherapy implantation has become the treatment of choice for early stage prostate cancer patients. Treatment of prostate cancer with radiation is traced back to 1909. Originally this treatment modality was very crude and could not gain much popularity till 1982. Advancements in radioactive source designs, introduction of new low energy radioactive sources, and new imaging modalities made this treatment modality a treatment of choice for early stage prostate cancer patients. Popularity of this modality is due to the fact that five-and ten-year disease control rates of brachytherapy are equal to those of the surgical, whereas, the toxicity and side-effects are perceived to be lower. This manuscript presents historical review of interstitial brachytherapy, innovations in radioactive source designs, dosimetry and dose calculations.
Keywords: Interstitial brachytherapy, advancements, Ra-226, Au-198, I-125, Pd-103, Cs-131.
Full-Text [PDF 513 kb]   (5420 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology


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Volume 5, Issue 4 (3-2008) Back to browse issues page