Rescue potency of Eucalyptus oil against gamma-rays induced gastric ulceration
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S. Tawfik , A. Elkady , S. Salama |
Health Radiation Research Department, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, P.O. Box: 29, Nasr City, Cairo, Egypt , samosoliman@gmail.com |
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Abstract: (1603 Views) |
Background: Eucalyptus oil often used for medicinal purposes. Aims: The Eucalyptus oil gastro protective impact investigated against gamma-rays-exposure-induced gastric ulceration in rats. Materials and Methods: Thirty-two rats were divided equally into 4groups; control, Eucalyptus oil (100mg/ kg), gamma-rays (7Gy) and Eucalyptus oil plus gamma-rays treated groups. The stomach histopathology samples were examined. The levels of malondialdehyde, reduced glutathione, superoxide dismutase, tumour necrosis factor-α and the interleukin-1β were assessed. Results: The stomach histopathological examination revealed that pre-treatment with Eucalyptus oil enhanced regeneration of mucosal crypt cells. The results revealed a decreased level of stomach malondialdehyde, inflammatory markers, increased levels of stomach antioxidants markers in Eucalyptus oil plus gamma-rays treated group. Conclusion: Eucalyptus oil ameliorates gamma-rays-induced gastric ulceration that could attribute to its antioxidant, anti-apoptotic and radioprotective activities.
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Keywords: Eucalyptus oil, gastric ulceration, gamma-rays, rats, radioprotector. |
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Full-Text [PDF 2182 kb]
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Type of Study: Original Research |
Subject:
Radiobiology
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