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Effect of low dose gamma-radiation upon Newcastle disease virus antibody level in chicken
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| M. Vilić, Ž. Gottstein, I. Ciglar Grozdanić, K. Matanović, S. Miljanić, H. Mazija, P. Kraljević |
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Abstract: (13644 Views) |
| Background: The specific antibody response
against Newcastle disease virus (NDV) in the blood
serum of chickens hatched from eggs exposed to low
dose gamma-radiation was studied. Materials and
methods: Two groups of eggs of commercial meat
chicken lines were irradiated with the dose of 0.30 Gy
60Co gamma-rays before incubation and on the 19th
day of incubation, respectively. The same number of
eggs unexposed to gamma-radiation served as
controls. After hatching the group of chicken hatched
from eggs irradiated on the 19th day of incubation
was not vaccinated while the group of chicken
hatched from eggs irradiated before incubation was
vaccinated on the 14 day. Specific serum anti-NDV
antibodies were quantified by the hemagglutination
inhibition assay with 4 HA units of NDV La Sota strain.
Result: Specific antibody titres against NDV in the
blood serum of chickens hatched from eggs
irradiated before incubation and vaccinated on the
14th day significantly increased on the 28th day.
Specific antibody titre against NDV in the blood
serum of chickens hatched from eggs irradiated on
the 19th day of incubation and non-vaccinated was
significantly higher on the 1st and 14th day.
Conclusion: Acute irradiation of heavy breeding
chicken eggs with the dose of 0.30 Gy 60Co gammarays
before incubation and on the 19th day of
incubation could have a stimulative effect on humoral
immunity in chickens. Iran. J. Radiat. Res., 2009 7 (1):
27-31 |
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| Keywords: Gamma-radiation, low dose effects, broiler, Newcastle disease virus, antibody. |
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Full-Text [PDF 376 kb]
(2772 Downloads)
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Type of Study: Original Research |
Subject:
Radiation Biology
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