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Acquiring molecular interference functions of X-ray coherent scattering for breast tissues by combination of simulation and experimental methods
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A. Chaparian   , M.A. Oghabian , V. Changizi |
| , chaparian@razi.tums.ac.ir |
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Abstract: (12005 Views) |
| Background: Recently, it has been indicated that
X-ray coherent scatter from biological tissues can be
used to access signature of tissue. Some scientists
are interested in studying this effect to get early
detection of breast cancer. Since experimental
methods for optimization are time consuming and
expensive, some scientists suggest using simulation.
Monte Carlo (MC) codes are the best option for
radiation simulation however, one permanent defect
with MC codes has been the lack of a sufficient
physical model for coherent (Rayleigh) scattering,
including molecular interference effects. Materials
and Methods: It was decided to obtain molecular
interference functions of coherent X-ray scattering for
normal breast tissues by combination of modeling
and experimental methods. A Monte Carlo simulation
program was written to simulate the angular distribution
of scattered photons for the normal breast tissue
samples. Moreover, experimental diffraction patterns
of these tissues were measured by means of energy
dispersive X-ray diffraction (EDXRD) method. The
simulation and experimental data were used to
obtain a tabulation of molecular interference
functions for breast tissues. Results: With this study a
tabulation of molecular interference functions for
normal breast tissues was prepared to facilitate the
simulation diffraction patterns of the tissues without
any experimental. Conclusion: The method may lead
to design new systems for early detection of breast
cancer. Iran. J. Radiat. Res., 2009 7 (2): 113-117 |
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| Keywords: X-ray coherent scattering, simulation, molecular interference functions, breast tissues. |
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Full-Text [PDF 528 kb]
(2857 Downloads)
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Type of Study: Short Report |
Subject:
Medical Physics
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