:: Volume 23, Issue 4 (10-2025) ::
Int J Radiat Res 2025, 23(4): 901-906 Back to browse issues page
Complications in CT-guided biopsy of tiny pulmonary nodules: a case-control study
G. Wang , P. Liu , X. Qubie , C. Fan , Y. Fang
Thoracic Surgery, Huoshan County Hospital, Anhui Province, China 237200 , wangguozhong8268@163.com
Abstract:   (1009 Views)
Background: This investigation explores the effectiveness and physiological consequences of CT-guided percutaneous lung biopsies, a common technique for analysing pulmonary nodules. Materials and Methods: The study involved a paired comparison involving 211 patients who received CT-guided lung biopsies and an equal number of matched controls who did not undergo the procedure. Variables such as demographic and baseline health characteristics, changes in cardiorespiratory parameters, and patient outcomes were meticulously recorded and analysed. Results: Both groups exhibited comparable baseline demographics and health statuses. The procedure confirmed the presence of malignancy or other diseases in 90% of cases (190 out of 211 patients). Significant physiological responses post-biopsy included elevated heart rate, increased systolic and diastolic blood pressure, enhanced respiratory rate, and reduced oxygen saturation levels, all statistically significant compared to controls. However, metrics such as hospital stay duration, rate of readmission within 30 days, and survival after one year showed no statistical difference between the groups. The incidence of complications following the biopsies was calculated at 15%. Conclusion: CT-guided percutaneous lung biopsy is a reliable diagnostic tool for pulmonary nodules, as evidenced by its high diagnostic yield. The procedure, however, leads to noticeable transient cardiorespiratory changes, underscoring the necessity for vigilant monitoring and supportive care during and after the procedure. Long-term patient outcomes did not differ significantly between the groups, indicating the procedure’s safety profile in a clinical setting.
Keywords: CT-guided percutaneous lung biopsy, diagnostic yield, cardiorespiratory changes, patient outcomes.
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Type of Study: Original Research | Subject: Radiation Biology



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Volume 23, Issue 4 (10-2025) Back to browse issues page