TY - JOUR T1 - Safe chemotherapy and targeted therapy for treating locally advanced NPC in a G6PD-deficient patient: case report and literature review TT - JF - Int-J-Radiat-Res JO - Int-J-Radiat-Res VL - 17 IS - 3 UR - http://ijrr.com/article-1-2613-en.html Y1 - 2019 SP - 505 EP - 508 KW - nasopharyngeal carcinoma KW - G6PD deficiency KW - chemotherapy KW - cetuximab KW - radiotherapy. N2 - The article was first report a case of a 32-year-old female with NPC that is G6PD-deficient. The patient completed induction chemotherapy and concomitant chemoradiotherapy successfully. The patient experienced grade 1 neutropenia , grade 1 diarrhea, and grade 2 acne-like skin reactions during the three cycles of induction chemotherapy. Grade 1 neutropenia, grade 1 diarrhea, grade 2 oral mucositis and grade 1 skin reactions were observed during the concomitant chemoradiotherapy. No hemolytic events were observed. We conclude that it is safe for G6PD-deficient patients with NPC to received chemotherapy and targeted therapy. M3 ER -