en Radiation Biology Radiation Biology تحقيق بديع Original Research <p><b>Background:</b> Keloids are benign fibrous dermal tumors originating from skin injury after surgery, piercing or others wounds. <b>Materials and Methods: </b>Sixty-two patients with keloids were treated postoperatively using orthovoltage irradiation. The total dose delivered was 12 Gy in three consecutive days, 4Gy per fraction. Treatment started 24 h after surgery. The median follow-up was 44.5 months. <b>Results:</b> Grade 1 erythema was observed in 48% of patients (30/62) 20/62 patients (32%) showed telangiectasia and altered skin pigmentation as late toxicities. In 10/62 (16%) a clinical relapse was observed. <b>Conclusion:</b> The postoperative orthovoltage radiotherapy for keloids is a valid and tolerated method that reduces the risk of recurrence. Aims: evaluate the role of post-operative superficial orthovoltage radiotherapy in the management of keloids.</p> Keloids, kilovoltage, radiotherapy 201 204 http://ijrr.com/browse.php?a_code=A-10-1-562&slc_lang=en&sid=1 A. Pontoriero apontoriero@unime.it 790031947532846009792 790031947532846009792 Yes Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy A. Potami 790031947532846009793 790031947532846009793 No A.O.U. “G. Martino” Operative Unit of Radiation Oncology, Messina, Italy G. Iatì 790031947532846009794 790031947532846009794 No A.O.U. “G. Martino” Operative Unit of Radiation Oncology, Messina, Italy S. Comitini 790031947532846009795 790031947532846009795 No A.O.U. “Cannizzaro” Department of Plastic Surgery, Catania, Italy M. Venza 790031947532846009796 790031947532846009796 No Department of Experimental Medical-Surgical, Specialized and Dentistry, University of Messina, Messina, Italy N. Settineri 790031947532846009797 790031947532846009797 No A.O.U. RR “Papardo-Piemonte” Department of Medical Physics, Messina, Italy S. Pergolizzi 790031947532846009798 790031947532846009798 No Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy C. De Renzis 790031947532846009799 790031947532846009799 No Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy