International Journal of Radiation Research
نشریه پرتو پژوه
Int J Radiat Res
Basic Sciences
http://ijrr.com
79
journal79
2322-3243
2345-4229
10.61186/ijrr
en
jalali
1396
4
1
gregorian
2017
7
1
15
3
online
1
fulltext
en
Dosimetric comparison of TomoDirect and TomoHelical plans in post-mastectomy chest wall radiation therapy
Radiation Biology
Radiation Biology
تحقيق بديع
Original Research
<div style="text-align: justify;">Background: The purpose of this study was to evaluate the characteristics of TomoDirect (TD) plans compared to conventional TomoHelical (TH) plans in chest wall irradiation in patients with breast cancer. Materials and Methods: TD and TH plans for only chest wall were retrospectively created for 30 patients previously treated with TH technique in our clinic. The beam angles were arranged to cover PTV chest wall and to minimize doses to OARs, ipsilateral lung and contralateral breast in TD plan. The prescribed dose was 50 Gy in 25 fractions. Results: The mean treatment times were similar in TH and TD (310.8 and 309 s, respectively, p> 0.05). There was no difference between the values of CI and HI of both plans (p>0.05). The values of Dmean, V5 and V20 of the ipsilateral lung in TD plan was significantly lower than that in TH plan for all 30 patients (p<0.001, p<0.001 and p=0.001, respectively). V25 and V30 values of the heart were significantly lower in TH than those in TD plan in left-sided chest wall irradiation (p=0.006 and p<0.001, respectively). However, V5 values in TH was significantly higher than those in TD (p<0.001). In the right-sided, there was no difference between two plans for V25 and V30 values of heart (p>0.05). Conclusion: Both of TH and TD plans produce acceptable target dose coverage in chest wall RT. Considering the risk of low-dose radiation to the critical organs; TD mode improve dose distribution.<br>
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</div>
Breast cancer, TomoDirect, TomoHelical, chest wall irradiation.
259
266
http://ijrr.com/browse.php?a_code=A-10-1-674&slc_lang=en&sid=1
F.
Teke
doktorfatmateke@gmail.com
7900319475328460015488
7900319475328460015488
Yes
Dicle University, Medical School, Department of Radiation Oncology, Yenişehir 21280 Diyarbakır, Turkey
H.M.
Doğan
7900319475328460015489
7900319475328460015489
No
Dicle University, Medical School, Department of Radiation Oncology, Yenişehir 21280 Diyarbakır, Turkey
M.A.
Kaya
7900319475328460015490
7900319475328460015490
No
Dicle University, Medical School, Department of Radiation Oncology, Yenişehir 21280 Diyarbakır, Turkey
M.
Gümüş
7900319475328460015491
7900319475328460015491
No
Dicle University, Medical School, Department of Radiation Oncology, Yenişehir 21280 Diyarbakır, Turkey