International Journal of Radiation Research
نشریه پرتو پژوه
Int J Radiat Res
Basic Sciences
http://ijrr.com
79
journal79
2322-3243
2345-4229
10.61186/ijrr
en
jalali
1398
3
1
gregorian
2019
6
1
17
3
online
1
fulltext
en
Demonstration of melorheostosis on bone scan
Radiation Biology
Radiation Biology
مطالعه موردي
Case Report
<div style="text-align: justify;">Background: Melorheostosis has been discussed infrequently in the nuclear medicine literature. A 25-year-old female patient presented with a one-year history of b:union: pain, sclerotic change and skin pigmentation on the left big toe interphalangeal joint. Ulceration, poor healing and hyperkeratoses of the wound were noted post debridement. The plain film of the left foot incidentally showed melorheostosis. Materials and Methods: Radiographs revealed cortical hyperostosis of big toe. After further evaluation by X-ray and bone scan of the left foot, the radiologic findings still indicated melorheostosis. A further Tc-99m MDP bone scan revealed extensive bone involvement in the left side of the pelvis and entire left lower extremity. Moreover, plain film whole body bone scan and MRI also revealed melorheostosis. Results: The clinical symptoms of her left big toe included interphalangeal joint callus formation, debridement, ulcer and hyperkeratoses. X-rays often reveal a pattern of thickened bone that resembles dripping candle wax, with periosteal cortical thickening, confined to sclerotomes; and can be seen apparently flowing across joints to the next bone. In the nuclear medicine image, an increase in radiotracer uptake is usually present on late phase bone scans. Conclusion: There was excellent correlation between the scintigraphic and radiographic distribution of these lesions in the following radiographs of pelvis, left femur, lower leg and MRI of the left foot. This study reported a rare case of melorheostosis affecting the big toe and reviewed the role of various imaging diagnosis of this rare bone dysplasia.</div>
Bone scan, melorheostosis, radiography, MRI.
521
525
http://ijrr.com/browse.php?a_code=A-10-1-813&slc_lang=en&sid=1
C.C.
Chang
7900319475328460014341
7900319475328460014341
No
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
Y.W.
Chuang
7900319475328460014342
7900319475328460014342
No
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
C.C.
Hsu
7900319475328460014343
7900319475328460014343
No
Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taiwan
C.Y.
Lin
7900319475328460014344
7900319475328460014344
No
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
Y.F.
Huang
7900319475328460014345
7900319475328460014345
No
Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
Y.M.A.
Chen
7900319475328460014346
7900319475328460014346
No
Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Taipei, Taiwan
Y.C.
Tyan
yctyan@kmu.edu.tw
7900319475328460014347
7900319475328460014347
Yes
Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan