en Radiation Biology Radiation Biology تحقيق بديع Original Research <span style="font-weight: bold"> Background: </span>Poorly educated people in some parts of Iran use burned mantles as a wound healing medicine. <span style="font-weight: bold">Materials and Methods: </span>To perform surface area measurement, twenty rats were divided randomly into two groups of 10 animals each. The first group received topical burned radioactive lantern mantle powder on the first to third days after making excision wounds. The second group received non-radioactive lantern mantle powder. For histological study, 36 male rats were randomly divided into two groups of 18 animals each. Full thickness excision wound (314±31.4 mm2) was made on the dorsal neck in all animals after inducing general anesthesia. For the first three days, cases had received topical application of the radioactive lantern mantle powder. Finally, to measure the tensile strength, an incision was made on the dorsal neck of the rats.<span style="font-weight: bold"> Results:</span> Surface area measurement of the wounds showed a progressive surface reduction in both groups. Histological study showed a significant statistically difference between cases and controls with respect to fibrinoid necrosis and neutrophilic exudate on days 3 and 14. Considering the existence of granulated tissue, a significant difference was observed between case and control groups on days 3 and 7. Tensile strength study showed no significant difference between the cases and controls. <span style="font-weight: bold">Conclusion:</span> Topical use of radioactive mantle powder can accelerate the healing process of the wound in rats. Lantern mantle, wound healing, radioactive, thorium. 97 102 http://ijrr.com/browse.php?a_code=A-10-1-279&slc_lang=en&sid=1 S.M.J. Mortazavi mmortazavi@sums.ac.ir 790031947532846001121 790031947532846001121 Yes M.R. Rahmani 790031947532846001122 790031947532846001122 No A. Rahnama 790031947532846001123 790031947532846001123 No A. Saeed-Pour 790031947532846001124 790031947532846001124 No E. Nouri 790031947532846001125 790031947532846001125 No N. Hosseini 790031947532846001126 790031947532846001126 No M.M. Aghaiee 790031947532846001127 790031947532846001127 No