en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Pigmented villonodular synovitis (PVNS) is a rare benign proliferative </span></span></span><a href="D://APP%E5%AE%89%E8%A3%85%E5%8C%85/Youdao/Dict/8.9.3.0/resultui/html/index.html#/ja<illegal tag>vascript:;"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="text-decoration:none"><span style="text-underline:none"><span style="language:en-US">disease</span></span></span></span></span></span></a><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US"> of the synovium which most commonly affects the knee. It is regarded as a benign disease, but has a local invasion. Postoperative adjuvant radiotherapy is very necessary for PVNS, but there is no consensus on the total dose of radiotherapy.&nbsp;</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Case presentation</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span>&nbsp;<span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A 22-year-old young male with diffuse PVNS of right knee was referred to our hospital with ongoing right knee swelling and limitation of motion of the knee. Preoperative magnetic resonance imaging (MRI) showed synovium of the joint was obviously thickened with multiple nodular low signals of long T1 and short T2 which is the typical characteristic of PVNS. The patient was treated with arthroscopic synovectomy combined with adjuvant postoperative low-dose external radiotherapy (20 Gy). </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusions</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span>&nbsp;<span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Based on related literature about radiotherapy of PVNS, arthroscopic synovectomy combined with postoperative low-dose external radiotherapy is an ideal treatment and prevents the recurrence for PVNS of the knee.</span></span></span></span></span></span></span></span></span></div> Case report, Pigmented villonodular synovitis, PVNS, Radiotherapy. 719 722 http://ijrr.com/browse.php?a_code=A-10-1-969&slc_lang=en&sid=1 J. Lai haixin27691@foxmail.com 7900319475328460022300 7900319475328460022300 Yes Department of Oncology, Jiujiang First People’s Hospital, Jiujiang, Jiangxi 332000, People’s Republic of China S. Hu 7900319475328460022301 7900319475328460022301 No Department of Infectious Diseases, Jiujiang Third People’s Hospital, Jiujiang, Jiangxi 332000, People’s Republic of China Y. Luo 7900319475328460022302 7900319475328460022302 No Department of Radiation Oncology, Yiwu Central Hospital, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang 322000, People‘s Republic of China R. Zheng 7900319475328460022303 7900319475328460022303 No Department of Radiation Oncology, Yiwu Central Hospital, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang 322000, People‘s Republic of China P. Chen 7900319475328460022304 7900319475328460022304 No Department of Radiation Oncology, Yiwu Central Hospital, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang 322000, People‘s Republic of China F. He 7900319475328460022305 7900319475328460022305 No Department of Radiation Oncology, Yiwu Central Hospital, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang 322000, People‘s Republic of China