en Radiation Biology Radiation Biology یادداشت فنی Technical Note <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The aim of the study was to compare the dose differences between 3D-printed bolus, commercial bolus (wax), thermoplastic mask bolus and bolus-free head phantoms simulating nose radiotherapy. </span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Materials and Methods</span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-GB">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">We used 3D printing technology to make a 3D-printed bolus. To evaluate the clinical feasibility, intensity-modulated radiation therapy (IMRT) plans were created for head phantoms that were 3D-printed bolus, commercial bolus (wax), thermoplastic mask bolus or bolus-free. Dosimetry differences were compared in simulating nose radiotherapy. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">: </span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">For the PTV of all the plans, 3D-printed bolus, commercial bolus (wax) and thermoplastic masks bolus had lower Dmax and D1% than the plan without the bolus; for Dmean and D95%, the results were the opposite. For V90%, V95%, V100% and HI, the plan with the 3D-printed bolus was better than the others, and the plan without the bolus was the worst. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusions</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The dosimetric differences of 3D-printed bolus, commercial bolus (wax), thermoplastic mask bolus and bolus-free were compared in head phantoms simulating nose radiotherapy. The 3D-printed bolus was good for fit, had a high level of comfort and repeatability, and also had better dose parameters in IMRT plans.</span></span></span></span></span></span></span></span></span></div> 3D-printed bolus, commercial bolus, IMRT, head phantoms, Dosimetric. 153 157 http://ijrr.com/browse.php?a_code=A-10-1-1019&slc_lang=en&sid=1 R. Song 7900319475328460023188 7900319475328460023188 No Department of Radiotherapy, Tianmen First People’s Hospital, Tianmen 431700, Hubei, China W. Li 609987176@qq.com 7900319475328460023189 7900319475328460023189 Yes Department of Radiotherapy, Tianmen First People’s Hospital, Tianmen 431700, Hubei, China