International Journal of Radiation Research

en A retrospective study on pre-operative CT-guided hook-wire localization of pulmonary nodules Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: The Background: Currently, surgical resection of the small and sub-centimeter pulmonary nodules (< 2 cm) is quite challenging via the thoracoscopic procedure. Our retrospective study aimed to evaluate the clinical efficiency of pre-operative CT-guided hook-wire localization of targeted pulmonary nodule patients prior to video-assisted thoracoscopic surgery (VATS) or surgery. Materials and Methods: 60 patients comprising pre-operative computed tomography (CT)-guided hook-wire localization of pulmonary nodules with < 2 cm diameter were retrospectively enrolled. Herein, we evaluated clinical variables, pathological outcomes, hook-wire localization procedure-related features, and complications from targeted pulmonary nodules patients. Results: Pre-operative CT-guided hook-wire localization was carried out successfully in 60 (100%) patients with wedge resection 41 (68%), segmentectomy 10 (16.7%), and lobectomy 9 (15%). Hook-wire localization procedure had mean time of 0.91±0.29 h, and 11 (18.3%) blood loss. All pulmonary nodule patients were positive pathological diagnoses for benign or malignant lesions, such as 5 (8.3%) benign lesions, 29 (48.3%) minimal adenocarcinoma (MIA) or invasive adenocarcinoma (IAC), and 21 (33.3%) adenocarcinoma in situ (AIS) malignant lesions. The majority of patients with hook-wire localization were either asymptomatic 19 (31.7%) or shown to have mild pain 25 (41.7%) and irritable cough 7 (11.7%). Conclusion: Preoperative CT-guided hook-wire localization of pulmonary nodules is safe and effective, which can reduce the operative time of targeted pulmonary nodules, and improvise the safety and outcomes of surgery.</div> Pulmonary nodules, computed tomography, thoracoscopy. 377 382 http://ijrr.com/browse.php?a_code=A-10-1-1055&slc_lang=en&sid=1 Z. Xu 7900319475328460024038 7900319475328460024038 No Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an223300, China Y. Ni 7900319475328460024039 7900319475328460024039 No Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an223300, China B. Gu 7900319475328460024040 7900319475328460024040 No Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an223300, China H. Zhou 7900319475328460024041 7900319475328460024041 No Department of Thoracic Surgery, Guanyun People’s Hospital, Guanyun222299, China Y. Luo 7900319475328460024042 7900319475328460024042 No Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an223300, China N. Li 7900319475328460024043 7900319475328460024043 No Department of Sanatorium 1, Air Force Health Care Center for Special Service Hangzhou Sanatorium 5, Hangzhou310002, China S. Chen chenshengnj@outlook.com 7900319475328460024044 7900319475328460024044 Yes Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an223300, China