International Journal of Radiation Research

en The application value of computed tomography perfusion imaging in diagnosing early cerebral infarction Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: To clarify the value of computed tomography (CT) perfusion (CTP) imaging in diagnosing early cerebral infarction (CI). Materials and Methods: Totally 100 suspected early CI patients in our hospital from May 2019 to May 2022 were selected and divided into observation and control groups based on examination methods, with 50 patients per group. In control group, patients received plain scanning through 64 row multi-slice spiral CT. On this basis, patients in observation group received CTP in certain area. Comparison of detection rate between groups was conducted. The observation indicators of CI patients detected by CTP in observation group were recorded and analyzed, including the mean transit time (MTT) of the same blood volume, cerebral blood flow (CBF), cerebral blood volume (CBV), and time to peak (TTP). The satisfaction with examination in both groups was explored. Results: CTP presented higher detection accuracy than plain CT scanning (P < 0.05). TTP presented elevation and MTT, CBV and CBF presented depletion in CI position than those in other cerebral position (P < 0.05). TTP, MTT, CBV and CBF presented statistical significance between ischemic penumbra (IP) position and CI position (P < 0.05). The satisfaction degree was elevated in observation group relative to control group (P < 0.05). Conclusion: CTP in early CI has higher diagnostic value and accuracy and elevates patient satisfaction, helping reduce disability and mortality. Additionally, CTP has high maneuverability and flexibility, and can measure IP, reducing the degree of brain tissue damage in patients, and is worthy of clinical application.</div> CT, perfusion imaging, cerebral infarction, detection accuracy, patient satisfaction. 139 143 http://ijrr.com/browse.php?a_code=A-10-1-1149&slc_lang=en&sid=1 B. Sun 7900319475328460025944 7900319475328460025944 No Department of Neurosurgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong 266035, China Z. Wang wzhigang202212@163.com 7900319475328460025945 7900319475328460025945 Yes Department of Neurosurgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong 266035, China