International Journal of Radiation Research
نشریه پرتو پژوه
Int J Radiat Res
Basic Sciences
http://ijrr.com
79
journal79
2322-3243
2345-4229
10.61186/ijrr
en
jalali
1388
3
1
gregorian
2009
6
1
7
1
online
1
fulltext
en
Rheological properties of blood after whole body gamma-irradiation
Radiation Biology
Radiation Biology
تحقيق بديع
Original Research
Background: The study of rheological properties
of blood has special interest since it is a circulating
fluid exposed to shear rates during its life time. This
work aims to investigate the influence of whole body
gamma irradiation on the rheological properties of
rat’s blood. The applied shear rate was from 12 to
375 s-1. Low shear viscosity (up to 100 s-1) depends
mainly on the erythrocytes aggregation while the high
shear viscosity depends on the erythrocytes deformability.
Materials and Methods: Adult male rats were
exposed to 1, 2.5, 3.5, 5, 7 and 9 Gy single doses.
The consistency index, apparent viscosity, yield stress
and aggregation index were increased after exposure
to gamma radiation. The dielectric properties of the
erythrocytes, in the low frequency range (60 Hz to 40
kHz), were measured in order to investigate the
changes in the membrane surface charge. Results:
The results obtained indicate that the viscosity,
consistency index and yield stress increased after the
exposure to the lowest dose taken 1 Gy, and
continued to increase as the exposure dose
increased up to dose 7 Gy and then decrease after
exposure to 9 Gy. The relative permittivity and
relaxation time showed significant decrease after
exposure to the lowest dose and continue to
decrease as the dose increased. Conclusion: The
obtained results can be attributed to the decrease of
membrane surface charge after exposure to gamma
radiation. The decrease in the membrane surface
charge is known to decrease the repulsion between
the cells and increase blood viscosity. Iran. J. Radiat.
Res., 2009 7 (1): 1117
Rheological properties, erythrocytes, gamma Radiation, aggregation.
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http://ijrr.com/browse.php?a_code=A-10-1-312&slc_lang=en&sid=1
N.S.
Selim
790031947532846001439
790031947532846001439
No
O.S.
Desouky
omardesouky@yahoo.com
790031947532846001440
790031947532846001440
Yes
S.M.
El-Marakby
790031947532846001441
790031947532846001441
No
I.H.
Ibrahim
790031947532846001442
790031947532846001442
No
H.A.
Ashry
790031947532846001443
790031947532846001443
No