en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">Plasma cell neoplasm is a group of disorders involving mature B-cells that results in excessive production of specific monoclonal heavy-chain immunoglobulins. Plasma cell neoplasm can present in different clinical forms.&nbsp;</span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Case Presentation:&nbsp;</span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">An elderly female presented with long-standing nasal congestion and was diagnosed with nasal plasmacytoma. After a complete checkup, including 2-[</span></span></span></span><span lang="en-GB" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">¹⁸</span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/ computed tomography (CT), a diagnosis of extramedullary nasal plasmacytoma with synchronous multiple myeloma was concluded. Herein, we report a single case of a patient with extramedullary nasal plasmacytoma and synchronous multiple myeloma, including its clinical and imaging findings.&nbsp; </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Conclusion: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">Multiple myeloma shows generally poor prognosis. Conversely, the prognosis of extramedullary plasmacytoma is good, and recurrence, metastasis, and transformation into multiple myeloma are rare. It is important to distinguish solitary plasmacytoma from other plasma cell diseases to choose the best treatment.&nbsp;A systemic understanding of the clinical and imaging features of extramedullary plasmacytoma and multiple myeloma are may help clinical and imaging doctors correctly diagnose the disease.</span></span></span></span></span></span></span></span></span></span></div> Extramedullary plasmacytoma, nasal cavity, multiple myeloma, 2-[18F]FDG, PET/CT. 235 237 http://ijrr.com/browse.php?a_code=A-10-1-1163&slc_lang=en&sid=1 M. Cheon diva1813@naver.com 7900319475328460026122 7900319475328460026122 Yes Department of Nuclear Medicine, Veterans Health Service Medical Center, 05368 Seoul, Republic of Korea J. Yoo 7900319475328460026123 7900319475328460026123 No Department of Nuclear Medicine, Veterans Health Service Medical Center, 05368 Seoul, Republic of Korea HS. Kim 7900319475328460026124 7900319475328460026124 No Division of Hematology and Oncology, Department of Internal Medicine, Veterans Health Service Center, 05368 Seoul, Republic of Korea