en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Metal Artifact Reduction (MAR) is very important in terms of dose calculation and optimization accuracy in radiotherapy (RT). There are many MAR programs available commercially.&nbsp; In this study, a MAR program was developed using MATLAB software (MATLAB-MAR), and the effect of the developed MATLAB-MAR on radiotherapy dose distribution was examined. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">In line with the purpose of the study, a phantom containing metal with a high atomic number (z=82) was created, and computer tomography (CT) of the phantom was taken. MAR developed with MATLAB software and a commercial metal artifact reduction (Smart-MAR) were applied on CT slices.&nbsp; The Hounsfield unit (HU), visually, artefact size and gamma evaluation effects of MATLAB-MAR, Smart-MAR and Without-MAR slices in the CMS XiO planning systems. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results:&nbsp; </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">As a result of the study, the best visually and HU improvement was seen in MATLAB-MAR. Moreover, in the dose distribution evaluation made by gamma analysis, an improvement was observed in MATLAB-MAR. </span></span></span></span></span></span></span></span></span></div> <span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Although similar values were obtained with MATLAB-MAR and the commercial software, it was determined that MATLAB-MAR was more advantageous than the commercial software in terms of being cost-free, providing results in a shorter time, not requiring reconstruction, and being open to development.</span></span></span></span></span></span></span></span></span> Metal artifact reduction, radiotherapy, gamma analysis, MATLAB. 367 372 http://ijrr.com/browse.php?a_code=A-10-1-1183&slc_lang=en&sid=1 A. Inal aysuntoy@yahoo.com 7900319475328460026968 7900319475328460026968 Yes Department of Radiation Oncology, Health of Science University, Antalya Training and Research Hospital, Kazım Karabekir Street, Muratpaşa, Antalya, Turkey S. Barlaz Us 7900319475328460026969 7900319475328460026969 No Department of Radiation Oncology, Mersin University School of Medicine Department, Çiftlikköy Kampüsü, Yenişehir, Mersin, Turkey