en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">To analyze the value of quantitative parameters of Computed Tomograph (CT)</span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">abdominal fat in predicting postoperative intestinal obstruction for gastric cancer. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A retrospective analysis was conducted on 120 gastric cancer patients treated between January 2017 and December 2021. These patients were divided into two groups: an observation group with postoperative intestinal obstruction (28 patients) and a control group without (92 patients). CT scans were used to measure the Subcutaneous Fat Area (SFA)</span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">and Visceral Fat Area(VFA)</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="language:en-US">, </span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">calculate the SFA-VFA difference, and the VFA/SFA ratio. The receiver operating curve (ROC) was employed to evaluate the predictive efficacy of these CT measurements. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The observation group exhibited significantly lower VFA and SFA compared to the control group (P < 0.05), while the differences in VFA/SFA ratio and SFA-VFA were not statistically significant. The area under the ROC curve (AUC) for the combined VFA and SFA in predicting postoperative intestinal obstruction was 0.902, with a 95% confidence interval of 0.859 to 0.956. This combined measure showed higher sensitivity (96.02%) and comparable specificity (85.24%) than single measurements. Logistic regression analysis identified diabetes, malnutrition, C-Reactive Protein (CRP)</span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">levels, VFA, and SFA as risk factors for postoperative intestinal obstruction (P < 0.05). </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The combined quantitative assessment of VFA and SFA using abdominal CT improves the sensitivity of predicting postoperative intestinal obstruction in gastric cancer patients. This complication is multifactorial, emphasizing the importance of a comprehensive approach in the clinical evaluation and management of these patients.</span></span></span></span></span></span></span></span></span></div> Abdominal CT, Fat quantitative parameters, Gastric cancer, ileus. 579 584 http://ijrr.com/browse.php?a_code=A-10-1-1211&slc_lang=en&sid=1 J. Yang 7900319475328460027905 7900319475328460027905 No Department of Gastrointestinal Tumor Surgery, Changxing County People's Hospital, Huzhou, China Y. Zhu 7900319475328460027906 7900319475328460027906 No Department of Gastrointestinal Tumor Surgery, Changxing County People's Hospital, Huzhou, China F. Wang 13868285853@139.com 7900319475328460027907 7900319475328460027907 Yes Department of Gastrointestinal Tumor Surgery, Changxing County People's Hospital, Huzhou, China