en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Integrated Positron Emission Tomography (PET) is widely used to diagnose, stage, and track human diseases during whole-body scanning. Standardized uptake values (SUV</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">_max</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">) of normal organs were evaluated by Fluorlne-18-Fluoro-2-doxyD-glucose [</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">¹⁸</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">F-FDG (PET/CT)] scanning. Multimodality imaging is an interesting area of research that aims to study the relationship between SUV</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">_max</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US"> in normal livers and different parameters determined with PET/CT. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A total of 100 people were tested for </span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">¹⁸</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">F-FDG PET/CT. All participants fasted for at least 6 hours before PET/CT imaging, and their fasting blood glucose levels were normal. Scans were acquired following an intravenous dose of </span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">¹⁸</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">F-FDG, and PET scans were collected 45-90 minutes after FDG injection. We measured the SUV</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">_max</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US"> in the livers of persons with normal BMI, high BMI, and obesity. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">After adjusting each SUV</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">_max</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US"> based on the results of the BMI calculation, which were determined for each subject based on their height and weight, the relationship between SUV</span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">_max</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US"> and BMI was statistically significant (p value < 0.05). The SUV measurement was greater in males than females, and it increased significantly in both male and female overweight and obese patients. Gender and BMI were the most reliable independent predictors of SUV value. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The hepatic absorption of </span></span></span><span lang="en-US" style="font-size:5.9939pt"><span style="font-family:Calibri"><span style="language:en-US">¹⁸</span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">FFDG increases with the patient&#39;s BMI. Patients&#39; genders are the independent variables that best predict their hepatic SUV values.</span></span></span></span></span></span></span></span></span></div> PET/CT, Standardized Uptake Value (SUV), Normal Liver, Body Weight. 831 835 http://ijrr.com/browse.php?a_code=A-10-1-1246&slc_lang=en&sid=1 S.M. Kadam 7900319475328460028383 7900319475328460028383 No Surgery Department, College of Medicine, University of Baghdad, Baghdad, Iraq M.M. Abbas 7900319475328460028384 7900319475328460028384 No Department of Radiology Techniques, Al-Hadi College, Baghdad, Iraq S.O. Issa 7900319475328460028385 7900319475328460028385 No Department of Physics, College of Science, University of Baghdad, Baghdad, Iraq