International Journal of Radiation Research

en Analysis of the accuracy of dynamic contrast-enhanced magnetic resonance imaging in assessing lymph node metastasis and prognosis in cervical cancer patients Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: To assess the accuracy, specificity, and sensitivity of dynamic contrast-enhanced magnetic resonance imaging (MRI) in assessing lymph node metastasis (LNM) and prognosis after cervical cancer surgery. Materials and Methods: Fifty cervical cancer patients admitted to our hospital from April 2022 to April 2023 were selected. 27 patients were in stage I-IIA and processed radical hysterectomy combined with pelvic lymph node dissection. Twenty-three patients were in stage IIB and beyond and underwent laparotomy with key site biopsy combined with pelvic lymph node biopsy. Postoperative pathological diagnosis was used as the gold standard for diagnosis. All patients underwent MRI scanning, including conventional MRI scanning such as DWI, T2WI, and T1WI of the pelvic cavity. Gadolinium-diethylene triamine pentaacetate (Gd-DTPA) was injected for dynamic contrast-enhanced scanning. The data of postoperative pathological staging, MRI staging, LNM, deep muscle layer invasion, and postoperative recurrence were analyzed. Results: There was no marked difference between MRI staging and postoperative pathological staging (P>0.05). When comparing preoperative clinical staging and MRI staging with postoperative pathological staging as the control group, there was no significant difference in accuracy. Both postoperative pathological diagnosis and MRI diagnosis had high specificity and sensitivity in assessing LNM and deep muscle layer invasion, but the differences were not significant (P>0.05). Conclusion: Dynamic contrast-enhanced MRI examination has high accuracy in assessing lymph node metastasis for cervical cancer patients. It has high sensitivity and specificity in assessing parametrial invasion, LNM, deep muscle layer invasion, and vaginal involvement, as well as has good prognostic value in assessing postoperative recurrence.  </div> Cervical neoplasm, neoplasm metastasis, magnetic resonance imaging, prognosis. 407 411 http://ijrr.com/browse.php?a_code=A-10-1-1343&slc_lang=en&sid=1 C.Y. Zheng 7900319475328460031111 7900319475328460031111 No Department of Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China Y.Y. Peng 7900319475328460031112 7900319475328460031112 No Department of Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China Z.Y. Zhang zhong71313852@163.com 7900319475328460031113 7900319475328460031113 Yes Department of Radiology, Shanghai First Maternity and Infant Hospital, Shanghai, China X.M. Zhang zhangxinm@zju.edu.cn 7900319475328460031114 7900319475328460031114 No Department of Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China