International Journal of Radiation Research

en Predicting patient-specific prostate motion using pelvic fat and pelvic cavity volume for prostate radiotherapy Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: The prediction of prostate motion is important for matching planned and delivered dose distributions in prostate radiotherapy. This study aimed to assess the relationship between anatomical characteristics and inter- and intra-fraction prostate motion. Materials and Methods: Sixty-six patients who underwent fiducial marker implantation were retrospectively evaluated. The anatomical characteristics (subcutaneous adipose tissue thickness, pelvic cavity volume, and fat volume of the lesser pelvis around the prostate), inter- and intra-fraction prostate motion, and standard deviations (SDs) in the anterior-posterior (AP), superior-inferior (SI), and left-right (LR) directions were determined, and their correlations were analyzed. Additionally, the three-dimensional (3D) distance between the coordinates of the center of gravity of the prostate and inferior margin of the symphysis pubis was calculated. Results: The pelvic cavity volume around the prostate exhibited a moderate correlation with the SD for inter-fraction prostate motion in the LR direction (r=0.47) and that for intra-fraction prostate motion in the AP and LR directions (r = 0.41, 0.52). The 3D distance between the coordinates of the center of gravity of the prostate and inferior margin of the symphysis pubis showed a moderate correlation with the average inter-fraction prostate motion in the AP direction (r=0.46). Conclusion: Prostate motion in the AP and LR directions may be related to the fat and pelvic cavity volumes around the prostate. The evaluation of anatomical characteristics can help predict patient-specific prostate motion during treatment planning.</div> Inter-fraction prostate motion, intra-fraction prostate motion, radiotherapy treatment planning, volumetric modulated arc therapy, anatomical characteristics. 421 426 http://ijrr.com/browse.php?a_code=A-10-1-1345&slc_lang=en&sid=1 A. Nakamoto 7900319475328460031133 7900319475328460031133 No Department of Radiology, Tokuyama Central Hospital, 1-1 Kodacho, Shunan, Yamaguchi, Japan Y. Tanabe tanabey@okayama-u.ac.jp 7900319475328460031134 7900319475328460031134 Yes Faculty of Medicine, Graduate School of Health Sciences, Okayama University, 2-5-1 Shikata, Kita-ku, Okayama, Japan K. Nishioka 7900319475328460031135 7900319475328460031135 No Department of Radiology, Tokuyama Central Hospital, 1-1 Kodacho, Shunan, Yamaguchi, Japan Y. Kunii 7900319475328460031136 7900319475328460031136 No Department of Radiology, Tokuyama Central Hospital, 1-1 Kodacho, Shunan, Yamaguchi, Japan A. Higashi 7900319475328460031137 7900319475328460031137 No Department of Radiology, Tokuyama Central Hospital, 1-1 Kodacho, Shunan, Yamaguchi, Japan H. Nishikawa 7900319475328460031138 7900319475328460031138 No Graduate School of Health Sciences, Department of Radiological Technology, Okayama University, 2-5-1, Shikata, Kita, Okayama, Japan R. Kawano 7900319475328460031139 7900319475328460031139 No Innovation Center for Translational Research, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, Japan H. Eto 7900319475328460031140 7900319475328460031140 No Department of Radiology, Yamaguchi University Hospital, 1-1-1 Minami Kogushi, Ube, Yamaguchi, Japan Y. Fuji 7900319475328460031141 7900319475328460031141 No Department of Radiology, Chugoku Central Hospital of the Mutual Aid Association of Public School Teachers, 148-13, Miyuki, Fukuyama, Hiroshima, Japan H. Aoyama 7900319475328460031142 7900319475328460031142 No Division of Radiological Technology, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama, Japan S. Yamada 7900319475328460031143 7900319475328460031143 No Department of Radiological Technology, Tsukuba International University, 6-20-1, Manabe, Tsuchiura, Ibaraki, Japan S. Takahashi 7900319475328460031144 7900319475328460031144 No Department of Radiology, Tokuyama Central Hospital, 1-1 Kodacho, Shunan, Yamaguchi, Japan