International Journal of Radiation Research

en A practical method of target volume delineation based on peritumoral edema in radiation therapy of glioblastoma Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: To introduce a simple glioblastoma (GBM) target delineation method based on peritumoral edema. Materials and Methods: A postoperative GBM patient was selected, the target volume was delineated using three methods, including the methods recommended by the Radiation Therapy Oncology Group (RTOG method), by the European Organization for Research and Treatment of Cancer (EORTC method) and by this study (New method), and radiotherapy plans were formulated by the same physicist. The dose distributions of each schedule were compared. Then, patients treated with the delineation method recommended in this study were retrospectively analyzed, and progression-free survival and overall survival were determined. Results: The distributions of the high-dose regions of the 3 plans were as follows: RTOG method > EORTC method > New method, as was the low-dose region. Thirty-three patients were included in this retrospective study, and the median progression-free survival (PFS) and overall survival (OS) were 12 and 25 months, respectively. Conclusions: Our study suggested that delineating the target volume for GBM radiotherapy based on peritumoral edema is a good choice.</div> Glioblastoma, Target volume, Delineating, Peritumoral edema. 473 480 http://ijrr.com/browse.php?a_code=A-10-1-1353&slc_lang=en&sid=1 H. Zhang 7900319475328460031168 7900319475328460031168 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China S. Hao 7900319475328460031169 7900319475328460031169 No Department of Nuclear Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China T. Wu 7900319475328460031170 7900319475328460031170 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China Y. Xu 7900319475328460031171 7900319475328460031171 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China D. Yang 7900319475328460031172 7900319475328460031172 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China Y. Sun 7900319475328460031173 7900319475328460031173 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China P. Zhang 7900319475328460031174 7900319475328460031174 No Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China Y. Yan yanyingdoctor@sina.com 7900319475328460031175 7900319475328460031175 Yes Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China