International Journal of Radiation Research

en Complications in CT-guided biopsy of tiny pulmonary nodules: a case-control study Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: This investigation explores the effectiveness and physiological consequences of CT-guided percutaneous lung biopsies, a common technique for analysing pulmonary nodules. Materials and Methods: The study involved a paired comparison involving 211 patients who received CT-guided lung biopsies and an equal number of matched controls who did not undergo the procedure. Variables such as demographic and baseline health characteristics, changes in cardiorespiratory parameters, and patient outcomes were meticulously recorded and analysed. Results: Both groups exhibited comparable baseline demographics and health statuses. The procedure confirmed the presence of malignancy or other diseases in 90% of cases (190 out of 211 patients). Significant physiological responses post-biopsy included elevated heart rate, increased systolic and diastolic blood pressure, enhanced respiratory rate, and reduced oxygen saturation levels, all statistically significant compared to controls. However, metrics such as hospital stay duration, rate of readmission within 30 days, and survival after one year showed no statistical difference between the groups. The incidence of complications following the biopsies was calculated at 15%. Conclusion: CT-guided percutaneous lung biopsy is a reliable diagnostic tool for pulmonary nodules, as evidenced by its high diagnostic yield. The procedure, however, leads to noticeable transient cardiorespiratory changes, underscoring the necessity for vigilant monitoring and supportive care during and after the procedure. Long-term patient outcomes did not differ significantly between the groups, indicating the procedure’s safety profile in a clinical setting.</div> CT-guided percutaneous lung biopsy, diagnostic yield, cardiorespiratory changes, patient outcomes. 901 906 http://ijrr.com/browse.php?a_code=A-10-1-1413&slc_lang=en&sid=1 G. Wang wangguozhong8268@163.com 7900319475328460032334 7900319475328460032334 Yes Thoracic Surgery, Huoshan County Hospital, Anhui Province, China 237200 P. Liu 7900319475328460032335 7900319475328460032335 No Medical imaging department, Armed Police Force Hospital of Sichuan, Leshan 614000, Sichuan province X. Qubie 7900319475328460032336 7900319475328460032336 No Medical imaging department, Armed Police Force Hospital of Sichuan, Leshan 614000, Sichuan province C. Fan 7900319475328460032337 7900319475328460032337 No Medical imaging department, Armed Police Force Hospital of Sichuan, Leshan 614000, Sichuan province Y. Fang 7900319475328460032338 7900319475328460032338 No Medical imaging department, Armed Police Force Hospital of Sichuan, Leshan 614000, Sichuan province