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:: Volume 17, Issue 3 (6-2019) ::
Int J Radiat Res 2019, 17(3): 497-500 Back to browse issues page
Safe chemotherapy and targeted therapy for  treating locally advanced NPC in a G6PD-deficient patient: case report and literature review
Y.M Jiang, X.D. Zhu PhD.,
Department of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning530021, People's Republic of China , zhuxiaodonggxmu@163.com
Abstract:   (65 Views)
The article was first report a case of a 32-year-old female with NPC that is G6PD-deficient. The patient completed induction chemotherapy and concomitant chemoradiotherapy successfully. The patient experienced grade 1 neutropenia , grade 1 diarrhea, and grade 2 acne-like skin reactions during the three cycles of  induction chemotherapy. Grade 1 neutropenia, grade 1 diarrhea, grade 2 oral mucositis  and grade 1  skin reactions were observed during the concomitant chemoradiotherapy. No hemolytic events were observed. We conclude that it is safe for G6PD-deficient patients with NPC to received chemotherapy and targeted therapy.
Keywords: nasopharyngeal carcinoma, G6PD deficiency, chemotherapy, cetuximab, radiotherapy.
Full-Text [PDF 1510 kb]   (39 Downloads)    
Type of Study: Case Report | Subject: Radiation Biology
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Jiang Y, Zhu X. Safe chemotherapy and targeted therapy for  treating locally advanced NPC in a G6PD-deficient patient: case report and literature review . Int J Radiat Res. 2019; 17 (3) :497-500
URL: http://ijrr.com/article-1-2613-en.html


Volume 17, Issue 3 (6-2019) Back to browse issues page
International Journal of Radiation Research
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